Similarly, Erivedge targets cancers in patients with mutations in a specific gene known as PTCH1.
Later, Kobilka isolated the specific gene that serves as a DNA blueprint for that adrenaline receptor.
WHITEHOUSE: Two American Scientists Win Nobel Prize in Chemistry
In order to operate, our cells constantly switch protein production on and off through specific gene functions.
But finding a specific gene is as difficult as reaching blindly into an oyster bed hoping to find a pearl.
The medicine basically undid five years of lung deterioration for patients who took it, but will only work for those whose CF is caused by a specific gene mutation.
Sangamo scientists have engineered a library of 10, 000 fingers by tinkering with the variable region, designing it so that it will seek out, recognize and bind to a specific segment of DNA for a specific gene.
An active gene produces a specific protein, but when the body has enough of that protein, the gene releases an inhibitor to stop production.
Herceptin is a breast cancer drug that was developed to treat tumors that have a specific mutation in the Her2 gene.
Instead of aiming at broad tumor categories, such as all patients with lung cancer or colon cancer, the new medicines target specific subsets of patients whose tumors have particular gene mutations.
Sir David expects that the company will put its first drug, one of a new type of gene-based drugs designed to combat specific cancer tumours, to clinical trial later this year.
The other method of genetically modifying a natural seed is to insert into it a gene that makes the crop tolerant to a specific herbicide, usually one the company makes itself.
The new drugs target very specific subsets of patients with the disease and will come with gene tests to pluck out which patients are likely to respond.
Gene therapy attempted to transport altered genes into the body to help fight specific diseases.
But there are only a few cases where we know the relationship of a specific mutation to a specific effect, and also only a small number of cases where an effect is determined by a single gene rather than the combined effects of hundreds or thousands of genes.
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