With that score the celebrated centre equalled Scotland great Ian Smith's championship try record of 24 from 78 years ago, while Ronan O'Gara's conversion saw the fly-half become the fifth man to reach 1000 Test points.
The second-half saw the introduction of Junior All Black fly-half Jimmy Gopperth in place of Rob Miller, and Bates said the former Blues half-back offered much needed stability and quality to the Falcons midfield.
Townsend started the campaign in the centre, but a broken leg for Duncan Hodge in the opener saw him move to fly-half and he proved a revelation with a try in every game.
Bresnan saw a top-edged hook fly over the wicketkeeper's head for four as England leapt up to second in the one-day rankings, but Pakistan will be hopeful of reversing their fortunes in the third match of the series at The Oval on Friday.
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The fly-half saw a drop-goal attempt come back off the upright on the resumption before South Africa were again reduced to 14 men.
"We're used to low-flying jets around here, " said George Pilkington, who saw the jet fly over his truck.
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London Irish led 6-0 after 15 minutes through two penalties from fly-half Hewat, before a spectacular solo try from Armitage saw him cut into a hole in midfield before outpacing the cover defence to score in the corner.
Uruguay keeper Nestor Muslera flapped at a cross, while opposite number Sergio Romero saw a clearance rebound off Uruguay forward Jorge Rodriguez - and he was relieved to see it fly wide.
The visitors' lacklustre play was epitomised when a well-worked free-kick saw Nani play in Evra on the left only for his low whipped ball to fly across the Villa goalmouth without a team-mate showing a desire to get to it.
But the fly-half, who missed five kicks at goal in the Basque country, saw his effort fall short as Biarritz surged into the semi-finals for the first time since 2006.
Saints fly-half Geraghty sliced a long-range drop-kick wide before O'Gara saw his penalty drop short of the post.
Masi is awarded the fly-half role after Ramiro Pez was dropped after Italy's disappointing World Cup campaign which saw them fail to qualify for the knock-out stages.
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