This is just one example of the profound differences between the sexes to drugs.

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"There are really quite profound differences as a function of how we live our lives, " she says.

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This, they believe, indicates profound differences in the way the disease was caused.

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There were differences, very profound differences, and yet there was still a sense I think that the differences between the parties could be bridged.

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And so this notion that somehow two different countries are going to have identical economic programs doesn't take into account profound differences in position.

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He also noted that "people have to be aware of very profound differences in copyright law, so you can't just transpose this project to other countries".

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The small differences in price in this narrow range are far more profound than bigger jumps higher up the cost spectrum.

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