It has been long believed that more profound differences could be discovered by studying how regions in the brain communicate with each other.

长期以来，研究人员相信通过研究大脑区域间如何交流可以发现患者和正常人之间更深层次的不同。

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"There are just very profound differences between Senator Lincoln and myself."

VOA: standard.2010.06.08

Final question, just to raise: I've talked in terms of the modular view but there might also be profound general differences between children and adults, not just specific to how you think about objects or how you think about people or how you think about this or how you think about that, but rather more general.

再说最后一个问题,我刚才是从模块理论的角度来讲述的,但在儿童与成人之间,或许还存在着深刻的一般性差异,不仅仅是具体到如何看待客体,如何看待他人,或是如何看待这个,如何看待那个,相反会更加一般化

耶鲁公开课 - 心理学导论课程节选

This is just one example of the profound differences between the sexes to drugs.

BBC: NEWS | Health | The dawn of gender-specific drugs

"There are really quite profound differences as a function of how we live our lives, " she says.

BBC: City living 'makes it harder to concentrate'

This, they believe, indicates profound differences in the way the disease was caused.

BBC: MS 'may be four different diseases'