"The body just doesn't take the pressure change that well, " he says.
Sheer weight of numbers helps to explain why there is pressure to change the law.
Mr Arafat is also under domestic pressure to change his ways, if not yet his leadership.
New York City's board of health and mental hygiene has resisted pressure to change its birth certificate policy.
He can respond to the pressure for change by trying to repress it, or by going with it.
Pressure to change the culture has been launched by Liberal Democrat MP Phil Willis and the trade union Unite.
They may well hold the key to regeneration of those town centres, so there is clearly pressure for change.
Doncaster admitted that the loss of one Champions League qualification spot next year would increase the pressure for change.
For the time being, though, the pressure for change comes mainly from Labour.
The disasters have highlighted dangerous conditions in one of the world's largest exporters of cheap clothing and heightened pressure for change.
This was welcomed by women's representatives, who nevertheless said that the pressure for change would still have to come from them.
Still, the very fact that Mr Ben Ali is going through the charade suggests that he is responding to pressure for change.
These days, however, the greatest pressure for change is coming from shareholders.
Bush is under added political pressure to change course in Iraq since the November 7 elections, when voters ended Republican control of Congress.
Plaid Cymru welcomed the electrification, and claimed it followed its pressure to change plans to electrify the track between London and Bristol only.
He says that if the company had shareholders, it would come under pressure to change the formula to enable it to be sold at supermarkets.
Most of the pressure for change, therefore, has come from abroad.
One pressure for change at the NYSE came from institutional investors.
As long as the Tour could boast a clean victor its bosses, cycling authorities and the riders themselves felt little pressure to change the status quo.
The real pressure for change is not coming from regulators, or banks, but rather from the market: cheque usage has been in slow decline for years.
So far, he's under remarkably little pressure to change course.
The pressure for change should, sooner or later, prove irresistible.
And as the parliamentary committee on the Treasury is also considering publishing a report on its recent investigation of the Scottish office budget, the pressure for change looks inescapable.
It serves to remind its readers why America changed its strategy in Afghanistan, and why the administration would be wrong to bow to pressure to change it back again.
And although the money spent on abstinence will probably be wasted, it is only one-fifteenth of the total and if its failure is manifest, then there will be pressure for change.
If these reforms are designed to make the contracts less speculative, the Treasury has resisted pressure to change contracts to explicitly penalise those investors who sell their PFI projects early to generate vast profits.
And the grumbling about vehicle fuel economy is getting loud enough that the U.S. Environmental Protection Agency is coming under pressure to change the way the fuel economy numbers are calculated, something it hasn't done since 1984.
"It will go on and on and on and you don't need to be Albert Einstein to know that affects the commercial attractiveness to us sponsors, " said Mr Fuller, a member of pressure group Change Cycling Now.
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