In animal tests Guilford's PARP inhibitors can reduce stroke-induced brain damage by up to 70%.

FORBES: Repairing The Brain

In animal tests Guilford's PARP inhibitors reduce stroke-induced brain damage by up to 70%.

FORBES: Repairing The Brain

Experiments at Snyder's lab and elsewhere have shown that excess levels of glutamate activate the mysterious PARP enzyme.

FORBES: Repairing The Brain

However, many scientists are already well advanced trying to make drugs which can inhibit PARP - the other enzyme which starts the signalling process.

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He said PARP-inhibitors might also be good for treating other forms of breast cancer that behave in a similar way, which account for a fifth of all breast tumours.

BBC: Image of breast cancer

By blocking these errant molecules, D-serine and poly ADP-ribose polymerase (PARP), researchers may be able to stop brain cells from dying while avoiding the toxic side effects that have plagued previous experimental treatments.

FORBES: Repairing The Brain

By blocking these errant molecules, called D-serine and poly ADP-ribose polymerase, known as PARP, researchers may be able to stop brain cells from dying, while avoiding the toxic side effects that have plagued previous experimental treatments.

FORBES: Repairing The Brain

Gleason also cites a new class of drugs known as PARP (poly ADP-ribose polymerase) inhibitors, which appear to be highly effective in treating breast cancer patients with certain mutations, and finally the sale of new products that could earn new markets.

FORBES

At Big Sur, it climbs up the rough volcanic ranges, carving around cliffs with sheer drops to the thrashing ocean below, and leads on to the silver-grey foreshores of San Simeon, where elephant seals parp and loll, wriggling to inch themselves up the sand as the frothing tide approaches.

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