• But a new category of drug called PARP inhibitors may change that.

    然而一种名叫PARP抑制剂的药物可能会改变现状。

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  • PARP inhibition may prove beneficial for the treatment of atherosclerosis.

    PARP抑制可能会被证实对动脉粥样硬化的治疗有帮助。

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  • Trapped PARP-DNA complexes have been shown to be cytotoxic to cancer cells.

    捕获PARP - DNA复合物已被证明对肿瘤细胞具有毒性。

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  • The first is that PARP-1, a protein found in every cell, becomes activated whenever a cell's DNA is damaged.

    第一是观察到PARP - 1存在于每个细胞中,并且当细胞DNA受损伤时能激活该蛋白质。

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  • To estimate the relative risk and the population attributable risk percent (PARP) of main risk factors by comprehensive analysis.

    利用综合分析方法估计我国人群三种肿瘤的主要危险因素的相对危险度及人群归因危险度百分比。

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  • Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to the caspase cleavage site in PARP.

    该多克隆抗体是采用合成的PARP裂解位点周围残基相对应的肽段免疫动物后制备获得。

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  • When DNA damages of cells appear, as a kind of molecular sensor of cells, PARP will recognize and bind to DNA breakages, then be activated.

    当细胞DNA发生损伤时,PARP可作为细胞内的分子感受器,识别、结合到DNA断裂处,并被激活。

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  • The study authors conclude that it is very likely that minocycline's neuroprotective and anti-inflammatory effects are due to PARP-1 inhibition.

    文章的作者总结道,二甲胺四环素的神经保护和抗炎作用很可能是由于抑制了PARP-1。

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  • This occurred in tumors that were PARP inhibitor-resistant from the start as well as those that initially responded to PARP inhibitors but became resistant later on.

    这种情况出现在开始就对PARP抑制剂耐药以及起初对PARP抑制剂有治疗反应,但后来耐药的肿瘤中。

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  • Objective: To observe the expression of poly (ADP-ribose) polymerase (PARP) in focal cerebral ischemia with reperfusion injury and explore the role of PARP in apoptosis.

    目的观察多聚ADP 核糖聚合酶(PARP)在脑缺血再灌流损伤中的表达,探讨PARP在细胞凋亡中的作用。

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  • We hypothesized that PARP may play an important role in atherogenesis and that its inhibition may attenuate atherosclerotic plaque development in an experimental model of atherosclerosis.

    我们假设PARP可能在动脉粥样硬化形成中起重要作用,它的抑制可能会减弱动脉粥样硬化实验模型中动脉硬化斑块的进展。

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  • It has been proved that PARP has lots of physiological and biochemistry functions and correlates with cell death. Many kinds of damage factors such as radiation may influence the activity of PARP.

    已经证实,PARP具有多种生理、生化功能,并与细胞的死亡相关,电离辐射等各种细胞损伤因素都可以影响parp活性。

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  • It has been proved that PARP has lots of physiological and biochemistry functions and correlates with cell death. Many kinds of damage factors such as radiation may influence the activity of PARP.

    已经证实,PARP具有多种生理、生化功能,并与细胞的死亡相关,电离辐射等各种细胞损伤因素都可以影响parp活性。

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