In essence, I believe this was not a failure of the drug or the mechanism but a failure of us as investigators to make sure we had sufficient disease in our population upon which totestour hypothesis--somewhat akin to trying to show one antibiotic is better than another or even a placebo, but selecting a population with no infection!
This is not just about more tests, because I know that in the past people have been concerned about, you know, is this about standardized tests, or are we going to have our young people being taught to the test?