This invited abuse from them, in much the same way that once isolated rhesus monkeys seemed to invite abuse from the colony.
But as the once-isolated island becomes more globally connected, its traditional diet faces greater competition.
His trip is the latest high-profile diplomatic visit to the once-isolated nation since a reformist government took office a year ago.
BBC: UN's Ban Ki-moon urges Burma to unite on path to change
These clerics who were once rather isolated in their little seminary town are now, they have the whole world open to them, and they have this sort of brain trust there.
China Mobile and Vodafone joined to bid for a mobile-telecommunications license in Myanmar, hoping to tap the nascent and highly lucrative sector as the once-isolated country opens up to foreign investment.
The five countries the Burmese president is visiting are not Europe's largest, but every step on the world stage involving this once most isolated of countries is carefully watched for signs of how well its democratic transformation is progressing, reports BBC South East Asia correspondent Jonathan Head.
Plasticity studies have also revealed that the five senses, once thought to be isolated systems in the brain, may be interchangeable.
The easy 2km trek passes through a series of isolated caverns once home to 15th-century hermits, which beg to be howled from. (Doing so produces a short, rich echo).
Once the best shots are isolated, the next step is making them even better.
Once a patient's cancer cells are isolated in the laboratory, the gene responsible for producing the antibody is extracted and added to the "tobacco mosaic virus".
Isolated on the western edge of Arizona, Quartzsite was once a mining area and way station for travelers, later becoming popular with retirees for its mild winters.
The only contact with the foreign Trailmen is through trade conducted once a year in silence and by sign language, since the isolated tribes are thought to have no common language.
Benito Ramos, of the national disaster agency, said the death toll was expected to rise once soldiers and police gained access to the far-flung villages isolated by floods, fallen trees and damaged communications.
She says her daughter and granddaughter are always "very busy working" and she felt incredibly isolated until Andrew, 44, started taking her out to the shops once a week.
In short, central and eastern Europe, whose nations once championed a strong relationship between their continent and America, could quickly become introverted, isolated and unhelpful.
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