Each letter will be read by detecting slight changes in the nanopore's electrical properties.

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Each letter will be read by detecting changes in the nanopore's electrical properties.

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Second, Jim Creamer, ILMN does not own 15% of Oxford, it has taken equity in the company and has absolutely NO IP on nanopore sequencing.

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In the case of Oxford Nanopore's technology, the DNA molecule is fed through the hole one base at a time by a second protein, an enzyme called an exonuclease.

ECONOMIST: Nanopores may lead the way to a new generation of sequencing

Another sign of how fast things are moving is the excitement being generated by Oxford Nanopore, a company that seeks to sequence DNA strands by pushing them through tiny holes.

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The concept is to place the membrane in a solution containing DNA and use opposing electrodes to force the DNA molecule through the nanopore at up to a million letters a second.

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The concept is to place the membrane in a solution containing DNA and use opposing electrodes to force the DNA molecule through the nanopore at up to 1 million letters per second.

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Now new entrants, like the Ion Torrent sequencing technology owned by Life Technology and the new types of sequencers being developed by Oxford Nanopore are fomenting more competition and driving costs down even further.

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That's the goal at a shop at Harvard, where Daniel Branton, a biophysicist, and his colleagues hope to design a better detector by passing DNA--a letter at a time--through a microscopic "nanopore" in a silicon membrane.

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That is the goal at a shop a few miles down the road from U.S. Genomics, at Harvard, where biophysicist Daniel Branton and colleagues hope to design a better detector by passing DNA, one letter at a time, through a microscopic "nanopore" in a silicon membrane.

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