The 700 patients in the ENHANCE trial, who all had a genetic disease causing their levels of bad cholesterol to spike without treatment, were all on the top dose of the cholesterol-lowering drug Zocor.

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Add in too many expensive benefits and premiums could spike to unaffordable levels.

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Short-term particle pollution measures the number of times in a year when levels spike above healthy standards for several days to several weeks.

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As fewer seats become available, fares switch to higher levels and if the carrier sees flights filling briskly, it will spike the prices.

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IP, or Internet Protocol, traffic returned to "near-normal performance levels within about an hour" after the spike in traffic shortly after the attacks occurred, said the Austin, Texas-based company.

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The danger is that there's no room to avoid Southern European debt levels if we have another recession or an interest-rate spike.

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Other applications will monitor other types of activity such as a spike in traffic to parts of web sites or a change in inventory levels and post notifications.

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