Catalonia, which already enjoys a large dose of devolution, has an election in the autumn.

ECONOMIST: The constitutional court limits Catalonia��s powers

But Mr Miliband insisted he always took anonymous quotes "with a very large dose of salt".

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Many advertising greats, often equipped with acute observational skills coupled with a large dose of empathy, always knew this.

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And the tissues surrounding the organ inevitably receive a large dose of radiation.

BBC: Surgery

The most unpleasant thing about the fashion for fun is that it is mixed with a large dose of coercion.

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Just recently, a third theory has entered the arena, that Alexander died from a maladministration of hellebore, a medicine that, if given in too large a dose, could also be a toxin.

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It takes much more than a large labor force and a dose of markets to assume the leadership of the global economy.

FORBES: Biglari Holdings

The bottom line: It takes much more than a large labor force and a dose of markets to become No 1 in the global economy.

FORBES: What It Takes For China To Be No 1

An acute dose is a relatively large amount of radiation received in a very short time period.

FORBES: Infographic: How Much Radiation Could You Survive?

The bottom line: A large population, a large labor force, and a dose of markets may be the necessary condition for leading the global economy.

FORBES: Why China Cannot Lead The Global Economy