The most unpleasant thing about the fashion for fun is that it is mixed with a large dose of coercion.

这种快乐的时尚最让人不悦的是随之而来的大量压制。

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The basic architectures do not look alike at all, though, and you must view any parallels with a large dose of skepticism.

但是，基本架构却一点都不像，而且必须慎重看待它的任何并行。

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MVC and MVD in large dose YHF group increased significantly compared with other groups(P<0.05) except small dose YHF group.

大剂量组梗死边缘区MVC、MVD明显升高，与其他各组（除小剂量组外）比较差异均有显著性意义（P<0.05）；

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Now, the polio vaccine that Salk produced was very effective, but it required a fairly large dose of the vaccine and it had to be injected into the arms of children.

索尔克生产的小儿麻痹症疫苗效果显著,但是,该疫苗的单支注射剂量非常大,而且必须通过小孩的手臂进行注射

耶鲁公开课 - 生物医学工程探索课程节选

So, even if the cost is small, $10 a dose, it quickly amounts to a large amount of money.

因此,即使单只成本很小,可能只有十美元,但是这很快就会累积成为很大的金额

耶鲁公开课 - 生物医学工程探索课程节选

Give enough of the vaccine so you have a dose for everybody in the world, or a large fraction of the people.

疫苗的数量,足以让世界上每个人都接种一支,或者让绝大多数人都能接种一支

耶鲁公开课 - 生物医学工程探索课程节选

Catalonia, which already enjoys a large dose of devolution, has an election in the autumn.

ECONOMIST: The constitutional court limits Catalonia��s powers

But Mr Miliband insisted he always took anonymous quotes "with a very large dose of salt".

BBC: MPs urge Brown to sack Miliband

Many advertising greats, often equipped with acute observational skills coupled with a large dose of empathy, always knew this.

FORBES: Nobody Buys an Ad: How Creativity Gets Results