Genasense, a melanoma drug, was rejected by a panel in 2004 after its maker, Genta, argued that although the drug failed to improve survival, it shrank tumors.
During the commodity boom in 2001-2008, it shrank by an average of 1% a year, whereas the world's other top 20 mining-export countries grew by an average of 5% a year.
Genasense, a melanoma drug, was rejected by a panel in 2004 after its maker, Genta (nasdaq: GNTA - news - people ), argued that although the drug failed to improve survival, it shrank tumors.
One of the big problems in getting approval for Erbitux, the cancer drug developed by ImClone (nasdaq: IMCL - news - people ) and Bristol-Myers Squibb (nyse: BMY - news - people ), was that it only had data showing it shrank tumors, not that it helped patients.
Between the presidential elections of 1960 and 2004, their share of the southern white male vote shrank by 17 points, but among non-southern whites it still shrank by 12 points.
ECONOMIST: The presidential election: White men can vote | The
At ASCO, Anthony Tolcher of the Institute for Drug Development in San Antonio, presented results from an initial trial showing that it dramatically shrank tumors in five of 41 patients tested.
Known then as ZD1839 and later named Iressa, it not only slowed the growth of tumors in animal tests, it actually shrank them--a surprise because the drug wasn't expected to kill cancer cells.
It shows Sutent shrank tumors by a third or more in 14% of 51 patients who were available for evaluation.
It is the only operating division whose profit contribution shrank in 2002 (see chart), and it has been hard to integrate its geekish internet culture, far removed from the Time Warner tradition.
When new methods came in a few years ago, the stated size of the epidemic shrank sharply and it became apparent that the annual rate of new infections had peaked in the late 1990s.
For millennia, the Atlantic Ocean had been a barrier cutting Europe off from the rest of the world, but Europe's new ships effectively shrank the ocean, turning it into a commercial highway.
It said the numbers suggested the UK economy shrank by 0.2% in the final three months of 2012.
But in two patients the cells stuck it out, and in those two the tumours shrank.
The UK shrank in the last two quarters, meaning it is back in recession.
Yet the economy shrank last year, and the government predicts it will decline an additional 2.2% this year.
During the recent minerals boom, production actually shrank by 1% a year, whereas it surged by an annual average of 5% in the rest of the world.
When the economy shrank again in the last quarter of 2012, it was by 0.3% and if there is a further contraction on Thursday then that will, in all likelihood, by relatively small.
The tax inspectors' union, Gestha, believes that it accounts for more than 23% of GDP and that it grew by 0.7% last year when recorded GDP shrank by 3.1%.
ECONOMIST: The jobless numbers get nearer to a grim milestone
That number shrank to just 28, 000 in 2004, but in 2011, it climbed to 40, 000.
For weeks, private soothsayers have been suggesting the Japanese economy shrank by an annualised 4% or so in that quarter, making it the third such decline in a row.
It turns out that the recession was then firmly under way: the latest data show GDP shrank by 1% in the second quarter of 2008.
Our government, as it grew, increasingly legislated to and for the large, as the number of small businesses shrank and were projected to continue to shrink.
The UK's economy shrank by 0.3% in the last three months of 2012, and if it contracts during the first quarter of this year then it will be back in recession for the third time in five years.
London (Financial Times) -- Britain's economy shrank 0.3 per cent in the final quarter of last year, increasing the likelihood it would slide into a "triple-dip" recession and piling pressure on the coalition government.
The economy shrank by 1.3% between January and March this year, the second quarter in a row it has declined.
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