• Sometimes Tim Loughton seems a little irritable.

    BBC: An elaborate ritual

  • Similarly, a former college athlete who becomes angry and irritable in his 40s could be suffering a midlife crisis or delayed reaction to head injuries sustained decades earlier.

    WSJ: Confusing Medical Ailments With Mental Illness

  • Of those, only Lotronex, a treatment for irritable-bowel syndrome in women, has been re-introduced.

    ECONOMIST: The best medicine? | The

  • According to these criteria, you must have certain signs and symptoms before a doctor diagnoses irritable bowel syndrome.

    CNN: Irritable bowel syndrome

  • Always worth noting: Placebos may have a big impact against irritable bowel syndrome and pain.

    FORBES: Nothing. Is It What Medicine's Missing?

  • You know, not irritable, but more directive in a helpful way.

    FORBES: Working Mothers - The Documentary

  • But in order for that to happen, Novartis has to convince gun-shy doctors that the drug is safe, and convince patients that abdominal pain and bloating are caused by a treatable ailment called irritable bowel syndrome.

    FORBES: Magazine Article

  • Last week, two studies from Sweden found that one hour a week of hypnotherapy for 12 weeks eased symptoms of irritable-bowel syndrome in 40% of patients (compared with 12% in a control group) and that the positive effects can last as long as seven years.

    WSJ: Medical Hypnosis: You Are Getting Very Healthy

  • The first drug for irritable bowel syndrome marked by constipation beat a year-long regulatory battle.

    FORBES: Novartis Calls Wonder Woman

  • Because there are usually no physical signs to definitively diagnose irritable bowel syndrome, diagnosis is often a process of elimination.

    CNN: Irritable bowel syndrome

  • Zelnorm, formerly known as Zelmac, treats irritable bowel disorder (IBS)--a combination of constipation, stomach pain and other severe symptoms that affects up to 15% of the population, mostly women.

    FORBES: Novartis Pushes Ahead On Pipeline Snags

  • Approval for Zelnorm, a treatment for painful constipation known as irritable bowel syndrome, was delayed on safety concerns.

    FORBES: Magazine Article

  • They are often told they have irritable bowel syndrome, but their symptoms improve on a gluten free diet (generally within one month).

    CNN: Are there degrees of gluten sensitivity?

  • My favorite illustration of this is a study written up by Harvard placebo researcher Ted Kaptchuk and colleagues in 2008 in the British Medical Journal. 262 patients with severe irritable bowel syndrome were randomly assigned to either be on a waiting list, to get fake acupuncture, or to get fake acupuncture accompanied by lots of warm talk.

    FORBES: How The Placebo Effect Will Help Allergan Sell Botox

  • The members of the group, which includes an urbane young doctor, a vain and verbose prosecutor, a Gogol-esque clerk with a laptop computer, and a punctilious military officer standing guard, grow increasingly irritable as they slog through lonely and uninviting terrain.

    NEWYORKER: Once Upon a Time in Anatolia

  • Its main claim was that even if y ou told someone you were giving them a placebo, it still worked better than nothing for irritable bowel syndrome.

    FORBES: Harvard Placebo Study Was Seriously Overhyped

  • Sufferers sleep for several days at a time, and when they wake up, they are irritable, ravenously hungry and sometimes hypersexual.

    WSJ: Unraveling the Riddle of Too Much Sleep

  • The FDA has announced that it has approved a new drug to treat chronic idiopathic constipation and to treat irritable bowel syndrome with constipation (IBS-C) in adults.

    FORBES: FDA Approves New Drug For Irritable Bowel Disorder (Update)

  • It said over a third of the population regularly suffer from digestive illnesses such as irritable bowel syndrome, constipation, diarrhoea, stomach-aches, nausea and sickness.

    BBC: NEWS | Health | People 'ignoring' gut illnesses

  • He was tight-lipped and irritable on the stump: so much so that several journalists covering his campaign mounted a brief boycott.

    ECONOMIST: The Philippines' election

  • And when a pregnancy begins on a traumatic note, stress could cause a woman to stay in a negative frame of mind for longer, making her feel harassed, irritable and moody and putting extra strain on her pregnancy.

    BBC: Royal baby: The three-month secrecy rule

  • The Swiss firm heralded it as a breakthrough for millions of people with stomach pain, indigestion and other symptoms of irritable bowel syndrome.

    FORBES: Crisis in the Cabinet

  • In an assessment backed by several of Clarke's colleagues in the Clinton administration, he is described by some in the Bush White House as a "my-way-or-the-highway type, " who can become irritable and difficult to work with if he does not believe his views are being heeded.

    CNN: Rice forcefully rebuts Clarke testimony

  • Clinical trials have indeed shown that probiotics (a mixture of bacteria found, for example, in yogurt) ease the symptoms of people with irritable-bowel syndrome, who often have slightly abnormal gut microbiomes.

    ECONOMIST: The human microbiome

  • Huffnagle explained that probiotics may help with a range of medical conditions including antibiotic-associated diarrhea, stomach flu in children and adults, irritable bowel syndrome, and even food and seasonal allergies in some cases.

    CNN: Can supplements block benefits of probiotics?

  • But in order to make Zelnorm a blockbuster, Novartis needs to get patients to go to the doctor and ask for help for their irritable bowel disorder.

    FORBES: Novartis Calls Wonder Woman

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