The prime minister, who will host Monday's summit, has pledged the UK's financial support for Gavi.
Rahim Kanani: What have been some of the milestones of impact for GAVI since its founding?
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In this model, GAVI works with pharmaceutical suppliers, donor governments, the World Bank, the Gates Foundation, UNICEF and WHO.
FORBES: GAVI Alliance CEO: Leadership Is About Vision and Responsibility, Not Power
Another organization, the GAVI Alliance, breaks down vaccine distribution by country and by drug (Gates is again a funder).
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Gavi's global immunisation programme includes plans to roll out new vaccines against major causes of pneumonia and diarrhoea, two of the biggest child killers.
To further goose competition, increase supply and bring down prices, GAVI encouraged drugmakers from developing nations like China and India to bid on contracts.
For example, in Italy's Piedmont region there are familiar white grapes like Moscato and Gavi, as well as lesser known varietals like Erbaluce and Arneis.
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And, Pfizer said it has entered into a second supply agreement to produce 480 million doses of the pheumococcal vaccine Prevenar 13 through 2013 with the GAVI Alliance.
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It is my responsibility, as the leader of GAVI, to make sure we are accountable for that goal and that we rely on data for our decision making.
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IFFIm helps GAVI but also provides a competitive financial return.
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The GAVI Alliance is a public-private approach to health funding.
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Gavi is a public-private partnership which draws together a number of organisations including the World Health Organization and the Bill and Melinda Gates Foundation, as well as the vaccine industry.
In his speech as GAVI host, Gates said he was stunned to hear half a million children a year were being killed by the rotavirus infection, a preventable form of gastroenteritis.
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Seth Berkley: The GAVI Alliance has achieved many things in its first dozen years, but none more important than helping save more than 5.5 million lives and prevent untold illness and suffering.
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Seth Berkley joined the GAVI Alliance as CEO in August 2011, as it launched its five year strategy to immunize a quarter of a billion children in the developing world with life-saving vaccines by 2015.
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Sensibly, it is not competing hard in the fashionable area of infectious disease, which is occupied not only by the Global Fund, PEPFAR and GAVI, but also by the (American) President's Malaria Initiative, the Gates Foundation and numerous bilateral deals between governments.
The Microsoft founder was speaking the day before he and Prime Minister David Cameron lead the Global Alliance for Vaccines and Immunisation (Gavi) conference, which will see political leaders discuss how to generate sufficient funds to ensure children in the world's poorest countries receive the vaccines they need.
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