For starters, such oversight provides a first-line of defense with frontrunning or insider trading issues.
' (nyse: AVE - news - people ) Allegra, as first-line treatment for allergies.
Utilization rates of between 20 and 30% of total capacity are common for first-line production storage systems.
Fibrates be used as a first-line drug to reduce triglycerides in patients at risk of triglyceride-induced pancreatitis.
In fact, in 2004 the American College of Obstetricians and Gynecologists issued guidelines calling the combination a first-line therapy.
Many analysts expect the two drug makers to eventually try to replace medicines like Glucovance as first-line treatments against diabetes.
Mr. Clinton's foundation had brokered discounts on first-line AIDS drugs, many of which were older and used relatively simple chemistry.
WSJ: Researchers Manipulate HIV Drug's Chemistry to Lower Cost
Instead, I get it from a large variety of online sources, with my first-line source being, of all things, Twitter.
If found to be infected, they would be put immediately onto a course of what are known as first-line antiretroviral drugs (ARVs).
And they expect Quad to become a widely used first-line therapy, since it consists of a single-tablet regimen and lacks neuropsychiatric side effects.
For the 3% or so of people per year for whom the first-line ARVs do not work, more expensive second-line treatments would be used.
"I'm reasserting that naproxen is a good first-line therapy, " he says.
On average, the drug extended survival by only two months from eleven months to thirteen months and that was in patients who, unlike Sara, had responded to first-line chemotherapy.
"It's concerning to us, because we're worried that patients who really aren't experts and read this casually could interpret that the ACC endorse this as a first-line therapy, " says Weaver.
Avastin will be for "first-line" use in patients after they are initially diagnosed with advanced colon cancer, while Erbitux will be used in patients who have already failed other drug regimens.
That communication became the model for delivering first-line healthcare.
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Ted Phillips, a specialist in MS at Texas Neurology who led some of the Tysabri trials, says he plans to mostly use Tysabri alone as the new first-line weapon against MS. His reason?
Three countries - Andorra, Iceland and Malta - had no cases of resistance to first-line drugs, while in the United States, Hong Kong and Cuba, the cases of MDR TB showed a decline.
BBC: Patients must complete a full course of drugs to cure TB
Over-the-counter products such as oral antihistamines and eye drops are a good first-line approach for people with mild allergies, says Dr. Stephen Canfield, an allergist at Columbia University Medical Center in New York City.
Some doctors have been using Vytorin as a first-line therapy because it's so easy to give: The lowest dose of this combo pill lowers cholesterol better than higher doses of the other medicines, with fewer side effects.
Infectious disease experts consider them to be an antibiotic of last resort, to be prescribed only when first-line antibiotics such as penicillin fail to work, or in cases of extreme, life-threatening infection, or for certain bacteria known to respond best to quinolones.
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Eloxatin was rejected by the Food and Drug Administration (FDA) in March 2000, because data submitted at the time failed to statistically prove that the new drug was better than the current first-line treatment, Pharmacia 's (nyse: PHA - news - people ) Camptosar.
"One of the lessons for companies trying to develop drugs is to listen to what the FDA tells you, " says Richard Goldberg , a professor of oncology at the Mayo Clinic, who is helping Sanofi run clinical tests that finally prove that Eloxatin should be the first-line drug against colorectal cancer.
Over the past two years, for instance, he has published studies maintaining the Chantix anti-smoking pill is unsuitable for first-line use (read here and here) and a meta-analysis indicating the mist form of the Spiriva inhaler that is used to treat chronic obstructive pulmonary disease had a 52 percent increase in mortality risk compared with a placebo ( see this).
FORBES: The Confusion Over A Pair Of Diabetes Drugs And Pancreatitis
"It says a lot that we've come here with more of a squad team and pushed what is probably their first-choice line-up, " he explained.
TaskRabbit nabbed the first-in-line spot to try to promote its online service that allows people to pay someone else to do a menial task for them.
Pilots will navigate the virtual racetrack projected as a tunnel onto a heads-up display while viewers at home will see the rockets superimposed onto the virtual course just like that yellow first-down-line you see while watching American Football.
PetMed Express posted a surprise fiscal third-quarter profit increase, the first bottom-line growth for the online-focused pet-medicine purveyor in more than a year, with revenue jumping 12% on a 29% surge in new orders.
Mr Jones has suggested that the newspaper was trying to pre-empt a judicial gag order by publishing first on-line.
Duda's grounder down the first-base line with runners on second and third hit the bag and caromed straight up in the air.
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