This year it is even more difficult, as the hoped-for economic recovery failed to materialize.
With HPV it is even more difficult, because cervical cancer takes years to develop.
And Wales legend Gareth Edwards says Wales are becoming even more difficult to beat.
Grieving is even more difficult when a loved one dies suddenly in traumatic circumstances.
But scientific information can be difficult to understand and even more difficult to explain to others.
And even more difficult if you go looking for solutions in the wrong directions.
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This may make it even more difficult for money market investors to keep pace with inflation.
His job is made even more difficult by the U.S.'s apparent fear of offending Israel.
Keeping them motivated may prove even more difficult than finding holes in the balance sheet.
It is even more difficult when trying to put pressure on the source of the problem.
However, managing critical email conversations is even more difficult for those programmed to communicate via email.
Once again the snow began to fall heavily and conditions became even more difficult for the players.
At the same time, the economy makes it even more difficult for women to leave abusive situations.
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Chancellor Angela Merkel has warned that the German economic climate in 2013 will be "even more difficult".
All of this makes life even more difficult for the central bank, despite its governor's cheery outlook.
These obscurities make the task of comparison-shopping for the most affordable and appropriate college even more difficult.
The task is made even more difficult by the phenomenon of "near money, " such as airline mileage rewards.
Those interventions, by shoring up stockmarkets with cheap money, have made life even more difficult for the bears.
By mid-November, the central and northern regions will be covered with snow, making road transport even more difficult.
"As difficult as it was for him at GM, it'll be even more difficult at Ford, " Tynan says.
California requires that 70% of the annual estimated taxes be paid by June 15, making predictions even more difficult.
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What makes some seemingly best practices even more difficult to uncover as harmful is that they can become self-perpetuating.
It was inevitable that these strategies would be hard to execute, and even more difficult to impose and monitor.
If Fabius and Fischer get their way, it will make success in a British euro referendum even more difficult.
Making the process even more difficult is their busy travel schedule, making it harder to keep an eye on things.
So much, after all, hinges on the outcome of the fiscal cliff situation, forecasting is even more difficult than usual.
This has made the flying experience even more difficult, particularly for the business travelers that provide most of the revenue.
Iranian cyber activists worry that the new tightening of rules will make their work even more difficult and expose their identities.
This is going to make a recovery in Japan even more difficult.
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Groupon would then profit from its own IPO and the valuing the stock then becomes even more difficult in a traditional sense.
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