Some, such as Synercid, which Aventis sold to King Pharmaceuticals today, are especially difficult to administer.
"It's very difficult to predict where and when these landslips are going to happen, " he said.
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It is not difficult to find couples like Lorenzo Barba and his wife Yolanda.
Scientist: I must confess, I find it difficult to believe in a disease of machinery.
Stand somewhere for a few minutes and it is difficult to avoid seeing something move.
O'Neill told the Racing Post how City Affair had proven difficult to control, even before it unseated him.
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It is difficult to know if unrest is growing, but the government at least seems to think so.
Bonner says Lam set the bar so high it was difficult to go after immigrant smugglers in court.
Marseille coach Didier Deschamps added that the postponement of the game "was difficult to understand".
Ireland coach Declan Kidney said it was difficult to assess O'Driscoll's contribution to Irish rugby.
And Wales legend Gareth Edwards says Wales are becoming even more difficult to beat.
As your salary increases in the corporate world, it becomes more and more difficult to quit.
She has the ability to make anything fun and finds it very difficult to sit still.
Those that have had very public embarrassments may find it more difficult to attract fresh capital.
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Countless genres are chemically fused, making it difficult to trace which ideas came from where.
He was notoriously difficult to please and viewed people and products in black and white terms.
Now I want you to think about one of those pesky, sometimes difficult to manage applications.
Such attacks are not necessarily a criminal offence and it can be difficult to bring prosecutions.
Every small business probably has stories about vendors who are particularly difficult to work with.
Such variety might be difficult to arrange in London, New York, Silicon Valley, or Mumbai.
It can be difficult to draw conclusions based on these reports, because they are random.
From a corporate governance standpoint, it is difficult to argue against more transparency, however.
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However, he hoped it would not be too difficult to get people visiting again.
It's all difficult to put into words and I want you to respect that.
Happily for researchers and indicative of the strides in this area they were not terribly difficult to identify.
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Now, policy members find it difficult to repeat many things that were said in March.
Information in these areas is often confusing, difficult to compare, and varies among markets.
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"It is incredibly difficult to mount a credible appeal from outside this country, " she said.
Remember that although the distinction can be difficult to draw, loneliness and solitude are different .
It would be difficult to ignore such an appeal from the pro-western Montenegrin government.
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