And the biggest blow to hopes for a Pacquiao-Mayweather superfight, which seemed feasible even a few short months ago, is simply that the bout is no longer as relevant or important as it was last week.
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That made it more of a middleweight bout, though no titles were at stake and none were needed before an appreciative crowd at the Mandalay Bay arena.
The latest bout of violence is no excuse for anyone to walk out of the multi-party talks.
At the end of the fifth round Camacho indicated he preferred not to continue, and the bout was ruled a no contest.
His 63rd career pro bout ahead, Hopkins has no interest in growing into another sad statistic.
The referee could also stop a bout when a fighter could no longer protect himself or lost consciousness.
The region may not be far away from a potentially harmful bout of tax competition, which would no doubt attract the ire of more established EU members such as Germany and France.
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For three months leading up to a bout, he will eat vegan, with no exceptions.
The oldest boxer to win a major title, the 48-year-old Hopkins said he could retire a champion if he's no longer inspired and the right bout doesn't materialize.
So, when a work crisis triggered a second bout of depression and panic attacks, he had no intention of trying meds again.
Pacquiao, who started life as a flyweight, will no doubt fight the winner of the bout between Floyd Mayweather Jr and Juan Manuel Marquez on 18 July.
Purdy, ranked No. 4 by the IBF, accepted the bout on four weeks' notice.
DeGale had no such trouble, opening the scoring in the middleweight bout with a chopping left, and he led 3-1 after the second round.
There are rumours of several large corporate bankruptcies, possibly only days or weeks away, that could produce a long overdue bout of honesty in the banking system, and leave the government with no choice but to act.
The defeat was veteran Thaxton's eighth in his 41-fight career but the Norwich fighter insisted afterwards he had no complaints with his corner's decision to withdraw him from the bout.
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