• Finally, it's the presence of antigen that determines how t cells migrate and interact with the tumor cells.

    最后一点,抗原的存在与否决定了T细胞如何迁移及能否作用于肿瘤细胞。

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  • Objective: to explore the expression characteristics of intracellular cytokines and surface costimulatory molecules in embryo antigen tolerant t cells transferred in pregnant mice.

    目的:分析过继转输的小鼠胚胎抗原耐受T细胞内细胞因子及细胞表面协同刺激分子的表达特征。

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  • Clone and express bradyzoite antigen 1(BAG1) gene of T. gondii, and analyze the immunoreactivity of the recombinant product.

    克隆与表达弓形虫缓殖子期特异性抗原1(BAG1)的基因,并分析重组抗原的免疫反应性。

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  • Cytotoxic t cells, after sensitization by antigen, are effector cells, especially important in antiviral immunity.

    已被抗原致敏的细胞毒性T细胞是效应细胞,在抗病毒免疫中起到特别重要的作用。

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  • When the T cells recognized the antigen, they interacted directly with the tumor cells.

    当T细胞识别肿瘤上的抗原时,这些细胞能直接与肿瘤细胞相互作用。

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  • In the absence of antigen, the t cells did not interact with tumor cells, and could not sustain an active migratory behavior within tumors.

    但是如果没有抗原的话,这些T细胞不能和肿瘤细胞相互作用,也不能在肿瘤组织内维持积极的迁移能力。

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  • Objective To investigate the association of cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) gene A/G polymorphism with susceptibility to diabetes mellitus in Han Chinese.

    目的探讨细胞毒T细胞相关抗原4 (CTLA 4 )基因A/G多态性与汉族人糖尿病易感性的关系。

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  • The cytokine profiles of these T cells were detected by antigen stimulated assay, ELISA and intracellular cytokine staining.

    分别应用抗原刺激试验、酶联免疫反应、细胞内细胞因子染色检测上述T细胞的细胞因子表达。

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  • The biological immune system employs B-Cell and T-Cell in detecting antigen.

    在机体免疫系统中,B淋巴细胞和T淋巴细胞协同起来识别抗原。

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  • Objective: to explore the anti-tumor effects of cytotoxic of T-lymphocytes (CTL) induced by dendritic cells (DC) vaccine loaded with tumor antigen.

    目的:探讨负载肿瘤抗原的树突状细胞(DC)疫苗诱导的细胞毒性T淋巴细胞(CTL)的体外杀瘤作用及对荷瘤小鼠的治疗作用。

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  • Objective to explore the feasibility that the recipient against donor antigen specific t lymphocytes clones are formed, and the suicide genes are induced into the clone.

    目的探索建立受体针对供体抗原特异性T淋巴细胞克隆,转入自杀基因诱导移植耐受的可行性。

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  • It is generally accepted that normal immune response to extrinsic antigens depends on coordinating interaction between t cells and antigen presenting cells (APCs).

    我们知道,人体对外来抗原的免疫应答依赖t细胞和特异性抗原递呈细胞(APC)之间协调的相互作用。

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  • It is suggested that acute leukemias associated with CD7 antigen may be come from different early t cells and myeloid cells.

    上述结果提示,伴有CD 7抗原表达的急性白血病实际上是T、粒等多种细胞来源的白血病。

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  • By pulling receptors away from their surface membrane during signaling, t cells can prevent themselves from being lethally overstimulated by too much antigen.

    在沟通过程中,T细胞会将受体抽离细胞膜表面,以避免因受到过多抗原的刺激而死于非命。

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  • Potentially misleading pathologic features in our series of extracavitary PEL included classic Hodgkin lymphoma-like features, lymph node sinus involvement, and T-cell antigen expression.

    在腔外PEL的病例中存在一些可能导致误诊的病理特征包括经典型霍奇金淋巴瘤样特征,淋巴结窦受累和T细胞抗原的表达。

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  • Therefore, in the process of producting T cell epitope, the antigen processing and presentation pathway plays a key role.

    因此,抗原的加工提呈过程对T细胞表位的产生起到决定性作用。

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  • Methods Expression of CD3, CD4 and CD8 antigen on peripheral blood t cells from 30 cases of hemodialysis and non-hemodialysis patients was evaluated by flow cytometry.

    方法应用流式细胞仪法检测30例透析及未透析患者外周血t细胞表面的CD 3、及其亚群cd4及CD 8抗原表达。

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  • In addition to the expression of antigen on its surface, activated t cell releases various kinds of active substances, including cytokines, to regulate series of immunological responses.

    细胞活化后除了表达细胞表面活化抗原外,主要释放多种活性物质发挥免疫调节功能,细胞因子是其中重要的一种。

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  • Methods Co culture systems of RPE cells with antigen specific t lymphocyte lines and resting t lymphocytes were established in vitro.

    方法建立RPE与抗原特异性T淋巴细胞系和静止淋巴细胞之间的共培养系统。

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  • Both the antigen and the T-helper lymphocyte recognition site containing constituent may be associated with the liposome by using hydrophobic interactions or by covalent attachment to a lipid.

    所述抗原和含有上述组分的T辅助淋巴细胞识别部位二者通过疏水相互作用或共价键附着到一个类脂上而与脂质体缔合。

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  • When their essential biological function as antigen-binding molecules and informers for T cells was unveiled, an explanation of why MHC also acts as major histocompatibility antigens was provided.

    随着其抗原结合分子及T细胞信使生物学功能本质的揭示,MHC为什么是主要组织相容性抗原的谜底就昭然于世。

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  • After capturing tumor antigen, DC migrates to TDLN where it becomes matured and starts presenting antigen, then induces t cell differentiation, maturation and to kill tumor cells.

    在捕获肿瘤抗原后,DC迁移至TDLN,发育成熟并递呈抗原,诱导T细胞分化、成熟,杀伤肿瘤细胞。

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  • It is very crucial to identify antigen peptide recognized by t cell to study adaptive immune response and immune regulation.

    确定T细胞所识别抗原分子上的短肽序列对T细胞表位进行定位,对于研究特异性免疫应答有着重要意义。

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  • They are able to suppress allogenic T-cell response and modify maturation of antigen-presenting cells.

    其能够抑制同种异体的T细胞的应答和修饰抗原呈递细胞的成熟。

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  • Antigen-specific immunological memory is a cardinal feature of immunity, which depends on generation and maintenance of memory t lymphocytes, B lymphocytes and plasma cells with antigen specificity.

    抗原特异性免疫记忆是免疫的基本特征,其物质基础是初次免疫应答后产生的抗原特异性的记忆性T淋巴细胞和记忆性B淋巴细胞以及浆细胞。

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  • They found it was a simple matter of Numbers: by wearing many hats, or antigen receptors, regulatory t cells can keep their eyes on a lot of different non-regulatory cells.

    他们发现通过戴帽子也就是说其携带的抗原受体,这就成了很简单的数字问题,因为调控T细胞可以盯住很多不同的非调控细胞。

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  • They found it was a simple matter of Numbers: by wearing many hats, or antigen receptors, regulatory t cells can keep their eyes on a lot of different non-regulatory cells.

    他们发现通过戴帽子也就是说其携带的抗原受体,这就成了很简单的数字问题,因为调控T细胞可以盯住很多不同的非调控细胞。

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