含有叶酸的聚合载体能够识别肿瘤表面受体,并且能够通过受体介导的(细胞)内摄作用转染细胞。
Polymeric carrier containing folic acid is expected to be able to identify tumor surface receptors and transfect cells by receptor-mediated endocytosis.
目的:探讨亚叶酸钙(CF)联合5氟胞嘧啶(5 FU)对转染胞嘧啶脱氨酶(CD)基因的直肠癌细胞的杀伤作用。
Objective to study antitumor effect of calcium folinate (CF) and 5 fluorocytosine (5 FU) on rectal carcinoma cells transfected with cytosine deaminase (CD) gene.
目的:评估质粒介导下蛋白涂层金属支架局部转染血管内皮生长因子(VEGF)基因对小型猪冠状动脉再狭窄的作用。
Objective: to assess the effects of local vascular endothelial growth factor (VEGF) transfer using protein coated metallic stents on restenosis of coronary arteries in mini swine model.
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