含有叶酸的聚合载体能够识别肿瘤表面受体，并且能够通过受体介导的(细胞)内摄作用转染细胞。
Polymeric carrier containing folic acid is expected to be able to identify tumor surface receptors and transfect cells by receptor-mediated endocytosis.
目的分析泛素依赖的蛋白水解通路(UPP)在转染了脊髓小脑性共济失调3型(SCA3)基因的PC 12细胞中的定位及作用。
Objective To analyze the role and location of ubiquitin-dependent proteolysis pathway (UPP) in PC12 cells transfected by plasmids with spinocerebellar ataxia type 3 (SCA3) gene.
目的：探讨亚叶酸钙(CF)联合5氟胞嘧啶(5FU)对转染胞嘧啶脱氨酶(CD)基因的直肠癌细胞的杀伤作用。
Objective to study antitumor effect of calcium folinate (CF) and 5 fluorocytosine (5 FU) on rectal carcinoma cells transfected with cytosine deaminase (CD) gene.
目的探讨白细胞介素23 (IL - 23)基因转染的树突状细胞(DC)负载凋亡癌细胞抗原后诱导的免疫应答对小鼠胰腺癌的治疗作用。
Objective to investigate the therapeutic effects on pancreatic carcinoma by dendritic cells (DCs) transfected with interleukin (IL) -23 and acquiring apoptotic cell antigen.
目的：评估质粒介导下蛋白涂层金属支架局部转染血管内皮生长因子(VEGF)基因对小型猪冠状动脉再狭窄的作用。
Objective: to assess the effects of local vascular endothelial growth factor (VEGF) transfer using protein coated metallic stents on restenosis of coronary arteries in mini swine model.
目的探讨反义vegf基因和内皮抑素基因联合转染在抑制肿瘤血管生成和肿瘤生长转移中的作用。
Objective to explore the co operative inhibitory effect of antisense VEGF gene and endostatin gene transfection on tumor angiogenesis, tumor growth and metastasis of lung cancer.
目的探讨全营养液(TNA)促进脂质体介导质粒dna转染结直肠癌细胞的作用。
Objective to study total nutrient admixture (TNA) promoting plasmid DNA transfection mediated with liposomes to colorectal cancer cells.
目的：研究人ice基因转染联合化疗药物诱导体外杀伤肝癌细胞的作用。
Objective: to investigate the cytotoxicity of ICE gene transfection in Combination with Antitumor Chemicals killing Hepatocellular Carcinoma Cells in vitro.
目的：探讨白细胞介素6 (IL - 6)基因转染的骨髓基质细胞系qxmsc1 IL - 6对骨髓移植后造血功能的重建作用。
Objective: to study the effect of the IL-6 transfected bone marrow stromal cell, QXMSC1 IL-6, on the hematopoietic reconstitution in bone marrow transplanted mice.
结果纳米颗粒转运系统能够保护被转运的基因，有较高的转染效率，具有良好的靶向性，并且提高了药物的生物利用度，显示出一定的缓控释作用。
Results Nanoparticle carrier system can protect the genes, have a high carrying efficiency and a well targeting property, it also can improve the bioavailability, sustained and controlled release.
目的在非免疫非肿瘤细胞中转染表达4 - 1bbl，并研究4 - 1bbl在调节淋巴细胞功能活性及抗肿瘤方面的作用和机制。
Objective: To express 4-1bbl in non-immunocytes and non-tumor cells and investigate the role of 4-1bbl in regulation of lymphocyte activity and antitumor effect.
目的：研究小鼠t淋巴细胞在转染嵌合性T细胞受体基因后的体外抗肿瘤作用。
Objective: to investigate the anti-tumor effects of murine T-lymphocytes harboring p185HER2 specific chimeric T-cell receptor gene.
目的：探讨B7 - 1基因转染骨肉瘤细胞能否诱导抗骨肉瘤主动免疫作用。
Objective: To explore whether transfection of osteosarcoma cells with B7-1 gene can induce anti-osteosarcoma active immune response.
结论MC148基因局部转染可能通过抑制器官移植后白细胞浸润而发挥免疫抑制作用。
Conclusion Local transfection of MC148 gene may promote immunosuppression by inhibiting leukocytic infiltration after allogeneous skin transplantation.
基因转染技术可克服外源性细胞因子在肌腱修复处作用短暂的不足。
A variety of gene transfer techniques can be used to maintain local concentrations of growth factor at tendon repair site.
结论：NGX6转染引起了一些非常重要的信号转导通路上的分子改变，可能通过参与调节这些信号转导通路而发挥其抗肿瘤增殖和转移的作用。
CONCLUSION: NGX6 transfection leads to molecular changes of some important signal pathways, and may suppress cell proliferation and metastasis of tumor by regulating these signal pathways.
LMP可明显抑制DMSO对CNE1细胞的诱导分化作用，转染细胞诱导后增殖力和角蛋白表达无显著改变（P＞0．05）。
The differentiation of CNE1 cells induced by DMSO was inhibited by LMP, there were no changes on the proliferation and keratin expression after induction of cells transfected by LMP gene ( P >0 05).
目的：探讨更昔洛韦对转染TK基因的骨髓瘤细胞生长的抑制作用。
Objective: To illustrate the effect on myeloma cells with TK gene by GCV.
目的建立NK细胞受体nkg2d真核表达载体，通过转染NK细胞系yt，初步探讨NKG2D分子对YT细胞系杀伤功能的增强作用。
Objective: to establish NK cell receptor NKG2D eukaryotic expression vector and investigate on the cytotoxicity of NK cell line-YT transfected with NKG2D.
通过直接肌肉内注射进行基因转染，p X1具有诱导肝癌细胞凋亡、抑制肝癌生长的作用。
The transfection of plasmid pX1 by injection into muscle of mouse could produce the inhibitory effect on liver carcinoma growth by inducing cells…
本文对近年来有关超声微泡造影剂作为基因转染载体的作用机制、影响因素、转染实验和应用等方面的研究作了总结。
This context concludes many researches about ultrasound microbubble: a novel gene vector in recent years. These researches include functional mechanism, influence factor, transfect...
将具有特殊生理功能的多肽作为基因或药物载体、或用于药物修饰等，可以提高基因转染效率，增强药物的靶向治疗效果，降低药物的毒副作用。
Due to the specific bioactivity of peptides, peptide-based gene and drug delivery systems could achieve improved gene transfection efficiency, enhanced drug targeting property and reduced side-effect.
结论：GST能改善突变型APP695基因转染引起的PC 12细胞病理变化，并提高其增殖能力，对转染细胞有一定的保护作用。
Conclusion: GST can decrease the apoptosis of PC12 cells induced by transfected with mutant APP695 plasmid DNA and enhance cells' proliferation, it may also has protective effects on neurons.
兔淋巴母细胞增殖实验证明转染后，表达的重组蛋白能够促兔外周淋巴细胞增殖作用，具有一定的生物学活性。
The expression products also to increase the proliferation of lymphoblast from the blood of rabbit, which has some biological activities.
结论：逆转录病毒介导的HSV -TK系统对人胃癌细胞有较高的转染效率，GCV对转染阳性的胃癌细胞有显著的杀伤作用。
Conclusion: transfection of gastric carcinoma with HSV-TK has higher transfection efficiency. MKN28TK cells are significantly sensitive to GCV.
结论：逆转录病毒介导的HSV -TK系统对人胃癌细胞有较高的转染效率，GCV对转染阳性的胃癌细胞有显著的杀伤作用。
Conclusion: transfection of gastric carcinoma with HSV-TK has higher transfection efficiency. MKN28TK cells are significantly sensitive to GCV.
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