目标基因替换是基因功能分析的重要手段。
Targeted gene replacement (TGR) is an important technique for gene function analysis.
通过对影响家族成员的LRP6基因测序，科学家发现了突变导致该基因产生的蛋白其中一个氨基酸替换了。
By sequencing the LRP6 gene in affected family members, the scientists found that the mutation caused the substitution of a single amino acid in the protein the gene produced.
然而医学研究者们表示这些细胞可能会从基因水平解释疾病的起源，而且将来可能成为组织更换的来源，其可以用来替换从脊髓损伤到糖尿病等疾病中的任何病变组织。
Medical researchers, however, say the cells may reveal the genetic origins of ailments and someday serve as sources of replacement tissues in everything from spinal cord injury to diabetes.
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