目前对动脉粥样硬化仍无好的治疗方法,主要是通过识别动脉粥样硬化不稳定斑块(unstable plaque)并及早临床干预,增强斑块的稳定性。而基因治疗(Gene therapy)是稳定动脉粥样硬化不稳定斑块很有前途的一种治疗方法。
基于300个网页-相关网页
...征(acute coronary syndrome，ACS)是心血管疾病患者发生心脏事件的主要理由，其发生的主要机制为不稳定斑块（Vulnerable plaque）的破裂并继发血栓，以而导致急性的血流减少或中断。
基于36个网页-相关网页
Conclusion: The uric acid may increase the carotid artery internal membrane unstable plaque area,then further causes the occurrence of cerebrovascular disease.
结论:尿酸可致颈动脉内膜不稳定斑块面积增大,从而进一步导致缺血性脑血管病的发生。
参考来源 - 缺血性脑血管病患者血清尿酸水平与颈动脉不稳定斑块的关系It is an important clinical issue to identify vulnerable plaque, predict the danger of ACS and prevent the happening of ACS.
如何识别不稳定斑块,预测ACS的危险性并预防ACS的发生是人们所面临的重要课题。
参考来源 - 急性冠脉综合征患者血清sCD40L升高的临床价值But our key issue at present is to discriminate the instability plaque ,carry out clinical intervention and enhance stability of the plaque. Gene therapy have a good future to stabilize atheromatous plaque.
目前存在的主要问题是识别不稳定斑块并及早临床干预,增强斑块的稳定性。
参考来源 - 靶向性造影剂携靶基因稳定动脉粥样硬化斑块的实验研究·2,447,543篇论文数据，部分数据来源于NoteExpress
人们已经建立多种自发或诱发的不稳定斑块的动物模型。
Spontaneous and induced animal models have been build to help us understand plaque vulnerability.
冠状动脉不稳定斑块破裂继发急性血栓形成是ACS的主要病理基础。
Acute coronary thrombus formation secondary to vulnerable atherosclerotic plaque is the main pathological basis of ACS.
研究背景急性冠状动脉综合征是由于不稳定斑块破裂诱发血栓形成所致。
Background Acute coronary syndromes are thought to result from atherosclerotic plaque disruption and intramural thrombus formation.
应用推荐