不稳定斑块的特征为T淋巴细胞和巨噬细胞的浸润。
Unstable plaque is characterized by an infiltrate of t cells and macrophages.
人们已经建立多种自发或诱发的不稳定斑块的动物模型。
Spontaneous and induced animal models have been build to help us understand plaque vulnerability.
因而寻找导致不稳定斑块形成与斑块破裂的危险因素具有重大意义。
It has great importance to search the risk factor that make the plaque unstable and rupture.
冠状动脉不稳定斑块破裂继发急性血栓形成是ACS的主要病理基础。
Acute coronary thrombus formation secondary to vulnerable atherosclerotic plaque is the main pathological basis of ACS.
研究背景急性冠状动脉综合征是由于不稳定斑块破裂诱发血栓形成所致。
Background Acute coronary syndromes are thought to result from atherosclerotic plaque disruption and intramural thrombus formation.
结论血管内超声检查可以准确诊断冠脉造影阴性冠心患者的不稳定斑块。
Conclusion The IVUS can get real diagnosis for those patients with ACS or CHD whose CAG is negative.
在内外因素的共同作用下，不稳定斑块可能发生破裂、糜烂以及钙化等现象。
Under the influence of intrinsic and extrinsic mediators, vulnerable plaque may develop to rupture, erosion or calcification.
结论：IVUS对冠心病冠状动脉粥样硬化不稳定斑块的诊断较CAG更具优势。
Conclusion IVUS is superior to CAG on the diagnosis of unstable arteriosclerosis plaques.
研究背景：急性冠状动脉综合征是由于冠状动脉的不稳定斑块破裂诱发血栓形成所致。
Background: Acute coronary syndromes are thought to result from atherosclerotic plaque disruption and intramural thrombus formation.
如何识别不稳定斑块，预测acs的危险性并预防ACS的发生是人们所面临的重要课题。
How to identify unstable plaques, predict the risk of ACS and prevent the ACS occur is an important problem facing people.
目的探讨增殖细胞核抗原(pcna)的表达和细胞凋亡在人冠状动脉不稳定斑块中的作用。
ObjectiveTo investigate the roles of apoptosis and express ion of PCNA in human vulnerable atherosclerotic plaque.
目的：研究表明炎症在冠心病患者不稳定斑块的发生、演变和斑块破裂过程中起着至关重要的作用。
Objective: Many study suggested that inflammation plays a crucial role in initiation, evolution and rupture of atherosclerotic plaque of coronary heart disease(CHD)patients.
结果15块破裂斑块中有12例PAPP-A染色阳性，而所有不稳定斑块与稳定斑块PAPP-A染色均为阴性。
Results PAPP-A staining was positive in 12 of 15 ruptured plaques, and negative in all unstable and stable plaques.
因此有学者提出，CD163/HO-1通路作为一个新的抗炎途径，有望在稳定动脉粥样硬化不稳定斑块中起着重要作用。
So, some scholar propose that CD163/HO-1 pathway is hopeful to play a critical role in atherosclerotic vulnerable plaque stabilization.
而炎症与免疫可能是导致斑块不稳定的主要因素。
The inflammation and immunity may be the main factors which lead to unstable plaque.
急性冠状动脉综合征(ACS)发生的成因主要由冠状动脉内不稳定的斑块形成及破损。
The unstable plaque rupture in coronary artery led acute coronary syndromes (ACS) to onset. After it, platelet activation resulted in the thrombosis.
结论：急性心肌梗死患者血清mcp 1水平明显增高，是显示斑块不稳定性的重要标志之一。
Conclusions: Serum MCP-1 level is elevated in acute myocardial infarction, indicating its role as a marker predicting the rupture of unstable plaques.
目的探讨缺血性脑血管病人颈动脉粥样硬化斑块不稳定性与脂质代谢异常间的关系。
Objective To explore the correlation between hyperlipemia, hyperlipoproteinemia and unstable plaques of carotid atherosclerosis in ischemic cerebrovascular patients.
动脉粥样硬化斑块不稳定是导致斑块破裂进而引起卒中的重要原因。
The instability of atherosclerotic plaques is the important reason that may result in plaque rupture and then cause stroke.
皮质支及动脉主干型脑梗死患者中不稳定性斑块35例，稳定性斑块9例；
There were 35 unstable plaques and 9 stable plaques in infarctions with the cortical branch and the stem of the artery.
动脉粥样硬化斑块的不稳定是导致斑块破裂、溃疡致使动脉内血栓形成从而引起卒中的主要发病机制，具有极大的危害性。
The instability of atherosclerotic plaques is the leading pathogenesis of stroke resulting in plaque rupture and ulcer-caused thrombosis and it is very harmful.
对于不稳定粥样硬化斑块的患者，往往更要促使其向稳定转化，以防止发生心肌梗塞及脑梗塞等。
For the unstable atherosclerotic plaque of patients, often more to promote its transformation to the stable to prevent the occurrence of myocardial infarction and cerebral infarction and so on.
目的：探讨缺血性脑血管病患者颈动脉粥样硬化斑块不稳定性与高血压、糖尿病、脉压等危险因素的关系。
Aim: To explore the relation between hypertension, diabetes and unstable plaques of carotid atherosclerosis in ischemic cerebrovascular patients.
能在不稳定冠脉斑块破裂前识别它吗？
Can We Identify Unstable Coronary Plaques Before They Rupture?
与静脉内超声相比，CT无法像静脉内超声一样确定斑块的成分，尤其是在决定哪些斑块是不稳定性斑块方面。
In comparison to IVUS, CT cannot ascertain the composition of the plaque as well as IVUS, especially for defining lesions that are likely to rupture, they explained.
有吸烟、高血压、糖尿病史者不稳定性斑块的发生率大于无以上病史者（均P〈0.05）；
The incidence of unstable plaques in the patients with smoking, hypertension and diabetes was higher than those without them(P < 0.05).
目的探讨缺血性脑血管病患者颈动脉粥样硬化斑块不稳定性的相关因素。
Objective to explore the relative factors of unstable plaques of carotid atherosclerosis in ischemic cerebrovascular patients.
近年来的研究表明，血管内皮生长因子、基质金属蛋白酶- 2和基质金属蛋白酶- 8在动脉粥样硬化斑块不稳定中起着重要作用。
Recent studies have suggested that vascular endothelial growth factor, matrix metalloproteinase-2 and-8 play important roles in the instability of atherosclerotic plaques.
近年来的研究表明，血管内皮生长因子、基质金属蛋白酶- 2和基质金属蛋白酶- 8在动脉粥样硬化斑块不稳定中起着重要作用。
Recent studies have suggested that vascular endothelial growth factor, matrix metalloproteinase-2 and-8 play important roles in the instability of atherosclerotic plaques.
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