The LDL receptor defects cause the elevation LDLcholesterol in plasma. This is the main reason for atherosclerosis and is closely related to the risk of coronary heart disease (CHD).

LDL受体介导的低密度脂蛋白胆固醇水平的升高是致动脉性粥样硬化的主要原因，与冠心病危险性的增加密切相关。

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Objective to investigate the effects of oxidized low-density lipoprotein receptor 1 (LOX-1) on secretion of adhesive molecules mediated by ox-LDL in human umbilical endothelial cells (HUVECs).

目的探讨血凝素样氧化低密度脂蛋白受体1 (LOX - 1)在氧化低密度脂蛋白(ox - LDL)诱导血管内皮细胞粘附分子表达中的作用。

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Early glycated low density lipoprotein (LDL) was not recognized by this receptor. AGEP BSA elevated cytosolic free calcium in a concentration dependent manner.

通过该受体介导，平滑肌细胞可内化、代谢AGEP．AGEP使胞浆游离钙呈浓度依赖性升高；

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Previous estimates said there were only 400 HoFH patients in the U.S. but included only those people confirmed to have two defective copies of the LDL receptor gene.

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