Depression is one of the leading problems of human mental imbalance and a common occur rence, which has an immeasurable negative impact on individual's physical and mental health, work and life.

抑郁是人类心理失调最主要和最经常出现的问题之一，对个体的身心健康、工作生活都会造成不可低估的负面影响。

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We cannot ignore the reality that more and more people are suffering from mental problems. One of the leading factors is that they do not communicate properly with their surroundings.

我们无法忽略这样一个事实：越来越多的人正在承受心理问题的折磨。造成这个现象的一个主要原因在于他们没有和周围的人进行适当的沟通。

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So the consigner can consign fake goods or the buyer can refuse to pay, leading to problems at all stages of the process.

因此，委托人可以委托拍卖假货，买家可以拒绝付款，使得整个拍卖过程的各个阶段都问题重重。

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The researchers disagree with the World Health Organization which says blindness and other vision problems are the leading cause.

VOA: special.2009.12.28

Uncorrected cases of near-sightedness, far-sightedness and astigmatism are the leading cause of vision problems.

VOA: special.2011.05.16

Toyota's problems come amid a growing number of complaints, accidents,recalls and financial problems for several leading Japanese companies.

VOA: standard.2010.02.15

In addition, as far as the prenatal environment per hormonal influences, there is some evidence that sexual, physical or verbal abuse could be factors rising to the level of stress that might alter the hormonal prenatal environment, leading to problems in neurodevelopment.

FORBES: Abuse Of Mom In Childhood And Autism Risk

In turn, such stepped-up oversight only uncovers more problems leading to more recalls.

FORBES: A Survival Map in the Age of Product Recalls

The first minister said discussions are taking place with local health managers to tackle any problems leading to inappropriate delays.

BBC: Photo of Scottish flag