That's why there's sort of a sense of loss and sadness.

这就是为什么这件事让人感觉失去了什么，令人难过。

youdao

When she died I was filled with a sense of loss.

她去世后我心里充满了失落感。

《牛津词典》

Many parents feel a sense of loss when their children leave home.

孩子们离家后许多父母都会有失落感。

youdao

And any argument between us would not cause me to lose heart or feel a sense of loss.

VOA: special.2010.07.11

Modern poetry arises, in Eliot's case, with the death of God, with the loss of a theological justification for life, with a sense of disenchantment, a sense of depletion, depletion of meaning and value.

在艾略特而言，现代诗歌的兴起，与对上帝信仰的消失，以及对生活不再在理论使其合理化，及人们的觉醒，对意义和价值的耗尽是相伴相随的。

耶鲁公开课 - 现代诗歌课程节选

And then Woodward argued quite directly that the loss of the Vietnam War began to liberate the South, in a sense that the South, Southerners, white Southerners, were the only Americans other than we always forget Native Americans who had ever lost a war.

接着沃德沃直截了当地说,越南战争的损失开始导致南方的解放,因为从某种程度上说,南方人,南方白种人,是美国唯一除了印第安人之外,我们总忽略这些北美原住民,输掉过战争的人

耶鲁公开课 - 美国内战与重建课程节选

But part of the passion reflected a sense of broader loss: a feeling that, with his death, the Senate had lost another member of its most endangered species, moderate Republicans.

ECONOMIST: Endangered species

Some of the symptoms of postpartum depression are the same as those for generalized depression, such as sadness, a sense of worthlessness and a loss of interest in sex or hobbies.

CNN: New dads can get postpartum depression, too

The MP's office said the wording of the Early Day Motion stated that the "the College authorities seem to have suffered a severe sense of humour loss and as a result penalised at least some of the students involved... worse, the College librarian has been sacked as a result of this incident for which the librarian bears no responsibility".

BBC: Oxford