...thylation-specific PCR (MSP) 共检查了三个基因 (FHIT, p16INK4a, and RARβ) 的启动子高度甲基化 (promoter hypermethylation)，并且侦测了八个微卫星序列 (D3S1234, D3S1285, D5S1456, D9S286, D9S942, GATA49D12, D13S170, and D17S786) 的异质性缺失 (lo...
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...癌基因失活与年龄相关 （age-related）的甲基化和癌特异性（cancer-specific）的 启动子高甲基化 （ promoter hypermethylation ）有关““，基因的表观遗传学调控机制在结直肠癌发生中的作用正 在逐渐被认识。
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Objective:To investigate the function of promoter hypermethylation of secreted frizzled-related protein 2(SFRP2) gene in colorectal cancer.
目的：研究分泌型卷曲相关蛋白2（SFRP2）基因启动子超甲基化与大肠癌的关系。
In muscle tissues, the promoter hypermethylation status of adiponectin gene was detected, which was consistent with the expression of this gene.
脂联素基因在猪肌肉组织中以高度甲基化状态为主，这一结果与该基因在肌肉组织中表达量相吻合。
The expression of p16 and DAPK protein were detected to analyse the relationship between the promoter hypermethylation and the loss of protein expression.
同时通过检测胃癌组织中基因的蛋白表达水平，了解基因高甲基化与其蛋白表达缺失之间的关系。
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