Objective:To investigate the function of promoter hypermethylation of secreted frizzled-related protein 2(SFRP2) gene in colorectal cancer.
目的：研究分泌型卷曲相关蛋白2（SFRP2）基因启动子超甲基化与大肠癌的关系。
In muscle tissues, the promoter hypermethylation status of adiponectin gene was detected, which was consistent with the expression of this gene.
脂联素基因在猪肌肉组织中以高度甲基化状态为主，这一结果与该基因在肌肉组织中表达量相吻合。
The expression of p16 and DAPK protein were detected to analyse the relationship between the promoter hypermethylation and the loss of protein expression.
同时通过检测胃癌组织中基因的蛋白表达水平，了解基因高甲基化与其蛋白表达缺失之间的关系。
Recent studies showed that ARF gene may play a role in tumorigenesis; the ARF gene promoter hypermethylation may be the principal mechanism in the inactivation of this gene.
目前研究表明ARF基因在肿瘤发生过程中可有起一定的作用，ARF基因功能的失活可能主要通过该基因启动子高度甲基化。
AIM: To investigate the hypermethylation of the BLU and ARF promoter in nasal NK/T cell lymphoma from nasopharyngeal mucosa and its roles in tumor genesis and molecular pathological diagnosis.
目的：检测BLU与ARF基因启动子在鼻NK/T细胞淋巴瘤中的甲基化状态，探讨其在肿瘤发生中的作用与分子病理诊断中的应用价值。
AIM: To investigate the hypermethylation of the BLU and ARF promoter in nasal NK/T cell lymphoma from nasopharyngeal mucosa and its roles in tumor genesis and molecular pathological diagnosis.
目的：检测BLU与ARF基因启动子在鼻NK/T细胞淋巴瘤中的甲基化状态，探讨其在肿瘤发生中的作用与分子病理诊断中的应用价值。
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