The relationship of codon 54 variation in intestinal fatty acid binding protein gene (FABP2) with NIDDM and its pathogenesis, and also with obesity, was investigated in 231 Chinese.
在231例中国人中观察小肠脂酸结合蛋白基因(FABP2) 54号密码子变异与NIDDM及其病理生理以及肥胖的关系。
Results The distribution of IRS1 gene polymorphism showed no difference between patients with NIDDM and normal controls.
结果IRS1基因多态性在NIDDM和正常人中的分布没有明显差异。
NIDDM were collected. Exon 17 ~ 21 of insulin receptor gene were amplified by PCR and screened by SSCP electrophoresis. After silver staining, the mutation samples were sequencing.
选择89例非胰岛素依赖性糖尿病(NIDDM)患者，扩增胰岛素受体基因的外显子17 - 21,sscp电泳，银染色后，对突变样品进行序列分析。
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