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小鼠的2 -细胞阻滞现象受细胞质内母型物质制约,具有品系依赖性。
The phenomenon of "2-cell block" is strain dependent, and is maternally restricted by cytoplasm.
结论:盼生安是周期特异性药物,通过将细胞阻滞于G1/G0 期而抑制其增殖。
CONCLUSIONS:Panshengan is a cell cycle-specific drug which can arrest the cells at G1/G0 phase.
添加新生牛血清的KSOM与胚胎培养液G1/G2均有效克服昆白小鼠2-细胞阻滞,并能得到较高的囊胚率。
The KSOM medium with 10% NBS and medium G1/G2 were effective to overcome the 2-cell block, and the blastocysts rate of the two groups were high.
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