小鼠的2 -细胞阻滞现象受细胞质内母型物质制约，具有品系依赖性。
The phenomenon of "2-cell block" is strain dependent, and is maternally restricted by cytoplasm.
结论：盼生安是周期特异性药物，通过将细胞阻滞于G1/G0期而抑制其增殖。
CONCLUSIONS:Panshengan is a cell cycle-specific drug which can arrest the cells at G1/G0 phase.
添加新生牛血清的KSOM与胚胎培养液G1/G2均有效克服昆白小鼠2-细胞阻滞，并能得到较高的囊胚率。
The KSOM medium with 10% NBS and medium G1/G2 were effective to overcome the 2-cell block, and the blastocysts rate of the two groups were high.
结论舒林酸的硫化代谢产物能够显著抑制血管内皮细胞的增殖活性，改变细胞的周期分布，使细胞阻滞于G 2期，并可能在此期诱导其凋亡。
Conclusions Sulfide can significantly reduce the proliferation of ECV304, change the cell cycle distribution and arrest cells in G2-M phase where apoptosis may be induced.
根据FDA提供的资料，拉帕替尼通过进入表达HER2蛋白的细胞，阻滞促进肿瘤生长的信号。
According to the FDA, Tykerb inhibits tumor growth by going inside cells containing the HER2 protein and blocking signals that promote tumor growth.
两种受测药物都是T型钙通道阻滞剂，它们能够抑制钙离子向神经细胞内的运动。
Both drugs tested are T-type calcium channel blockers, which inhibit the movement of calcium ions into nerve cells.
代之以衰老为特征的细胞周期阻滞的表现。
Instead the cells underwent cell cycle arrest with features of senescence.
结果：两种药物均具有抗qgy细胞增殖、阻滞细胞周期、诱导凋亡及抑制端粒酶活性的作用。
Results: These two drugs could inhibit the proliferation of QGY cells, block the cell cycle, induce its apoptosis and inhibit the activity of telomerase.
研究人员还怀疑单纯阻滞CD47是否足以消灭肿瘤细胞。
The researchers also questioned whether simply blocking CD47 would be enough to bring on a cell's destruction.
近年来实施的研究发现在放疗的同事一定种类的细胞因子被阻滞，各种癌症对放疗的反应要更好。
Studies conducted in recent years found that response to radiation therapy in various cancers is better when certain types of cellular growth factors are blocked at the same time.
目的研究钙通道阻滞剂是否减轻低温保存下肝细胞的钙超载并起到保护肝脏的作用。
Objective to study whether the calcium channel blockers can alleviate calcium overload to protect liver function during cold storage.
目的研究茶多酚诱导肺癌细胞凋亡的作用及其对细胞周期的阻滞作用。
Objective to evaluate the effects of tea polyphenols on the induction of apoptosis and blockage of cell cycle.
目的研究氯通道阻滞剂对肾小球系膜细胞增殖的作用。
Aim To investigate effects of chloride channel blockers on proliferation of mesangial cells.
河豚毒素为强效钠通道阻滞剂，它可通过阻断钠通道而影响细胞膜动作电位的产生。
Tetrodotoxin (TTX) is a potent sodium channel blocker. It can affect the generation of action potentials of cell membranes by blocking sodium channel.
结论平瘤康含药血清可能通过阻滞细胞周期而抑制胶质瘤细胞增殖。
Conclusion the Pingliukang medicated serum can inhibit the proliferation and block cell cycle of cultured C6 glioma cells.
细胞凋亡过程阻滞与细胞增殖异常一样，是肿瘤发生的主要机制之一。
The block of cell apoptosis is one of the important mechanisms as the same as the abnormality of cell proliferation in carcinogenesis.
一旦TP53蛋白被激活就能引发数种基因的表达来影响细胞周期阻滞、DNA修复、或者在DNA修复失败后引导凋亡发生。
Once the TP53 protein is activated, it can trigger the expression of several genes that influence cell cycle arrest and DNA repair or lead to apoptosis when DNA repair is failed.
作为DNA损伤剂，LDM可以诱导细胞周期阻滞、凋亡和裂亡。
Like other DNA damage agents, LDM induces cell cycle arrest, apoptosis and mitotic cell death.
目的：氟桂利嗪是通过血脑屏障的细胞钙超载阻滞剂。
AIM: Flunarizine is a blocker for calcium overload of cells, which could pass blood brain barrier.
预防性应用尼莫地平可阻滞或减轻细胞内钙超载，同时还可保护细胞膜膜泵活性。
Being used prophylactically, nimodipine can prevent or relieve calcium overload, and can also protect membrane pump activities of cell membrane.
大多数应用于临床的局麻药物都是相对疏水性的分子，可弥散通过细胞膜，作用于阻滞部位的钠通道。
Most local anaesthetics used clinically are relatively hydrophobic molecules that gain access to their blocking site on the sodium channel by diffusing into or through the cell membrane.
钙通道阻滞剂硝苯地平可阻止过多的钙进入细胞内，从而纠正低钙血症。
A calcium channel blockade nifedipine may block translocation of calcium from extracellular to intracellular compartments, thus correct hypocalcemia.
苦参碱可能是通过将人肝癌细胞周期阻滞在G0～G1期，抑制其增殖，通过诱导人肝癌细胞发生凋亡等，发挥其抗肝癌作用。
Matrine inhibits the proliferation of the cells by blocking the hepatocarcinoma cell cycle to G0-G1 phase, and develops its anti-hepatocarcinoma function by inducing human BEL-7402 cells apoptosis.
该药能阻滞癌细胞上的受体，正常情况下，这些受体与雌激素相连，因此这种药能阻止雌激素刺激肿瘤的生长。
The drug blocks receptors on cancer cells that normally bind with estrogen, and thereby prevents estrogen from stimulating tumors to grow.
因此，ATM特异性阻滞剂ku55933可以在原代T细胞中抑制HIV复制。
Thus, the ATM-specific inhibitor ku55933 can inhibit HIV replication in primary t cells.
结论PTEN过度表达将引起肾脏成纤维细胞周期G 1期阻滞，这一过程与PTEN在细胞核定位有关。
Conclusion Overexpression of PTEN will induce G1 arrest in rar renal fibroblast cells, which associated with the nuclear location of PTEN.
研究发现，许多天然植物成分能诱导肿瘤细胞凋亡，并能使肿瘤细胞发生细胞周期阻滞，抑制肿瘤细胞增殖。
It is well known that many natural products inhibit tumor cell proliferation by inducing apoptosis and blocking cell cycle.
流式细胞术结果显示：转染e1 A基因后，细胞周期出现S期抑制，G 2期阻滞。
Flow cytometry revealed that E1A transfection induced s stage suppression and G2 stage arrest in Hela cells.
这种药物可针对细胞内的关键靶信号途径从而阻滞或延缓肿瘤生长。
Such drugs target key signaling pathways within cells that can stop or slow tumor growth.
结论：本研究首次证实白花丹醌能够抑制APL细胞系nb4的增殖、诱导细胞凋亡及阻滞细胞周期进程。
It is concluded that for the first time the present study shows that plumbagin can inhibit cell proliferation, block cell cycle and induce apoptosis of APL cell line NB4 cells.
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