介绍组合生物合成技术在药物发现中的应用情况及研究进展。
The applications and the progress in new drug discovery of combinatorial biosynthesis technique were introduced.
组合生物合成是在抗生素产生菌的次级代谢产物合成途径中涉及到的一些酶的编码基因之间的互换，从而产生许多新的“非天然的天然化合物”。
Combinatorial biosynthesis can produce new "unnatural" natural products through exchange of genes encoding the enzymes involved in secondary metabolites biosynthesis pathway in antibiotics producers.
阿维拉霉菌是一种什么性质的抗生素，现有的研究成果将有助于采用组合生物合成方法进行阿维拉霉素的分子改造与修饰，从而产生新的阿维拉霉素衍生物。
Avilamycin quality have what kind of quality, the existing returns will help to alter or decorate it's molecule by the Combinatorial biosynthesis method, and produce new ramification of Avilamycin.
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