介绍组合生物合成技术在药物发现中的应用情况及研究进展。
The applications and the progress in new drug discovery of combinatorial biosynthesis technique were introduced.
组合生物合成是在抗生素产生菌的次级代谢产物合成途径中涉及到的一些酶的编码基因之间的互换,从而产生许多新的“非天然的天然化合物”。
Combinatorial biosynthesis can produce new "unnatural" natural products through exchange of genes encoding the enzymes involved in secondary metabolites biosynthesis pathway in antibiotics producers.
阿维拉霉菌是一种什么性质的抗生素,现有的研究成果将有助于采用组合生物合成方法进行阿维拉霉素的分子改造与修饰,从而产生新的阿维拉霉素衍生物。
Avilamycin quality have what kind of quality, the existing returns will help to alter or decorate it's molecule by the Combinatorial biosynthesis method, and produce new ramification of Avilamycin.
因此了解这些蛋白质是如何正确组合成的成为了理解生物化学过程和新药发明的关键所在。
Figuring out how they fold correctly is thus crucial to understanding biochemical processes, and to creating new drugs.
依照科学家的观念,生命起始于化学产生生物之际,也就是说,在一些简单的分子组合成更复杂的分子并开始进行自我复制之时。
According to scientists, life began when chemistry begat biology-that is, when simple molecules assembled into more complex molecules that then began to self-replicate.
在实验室,他们将共同生活在同一微生物环境里基因相似的细菌组合成一组。
In the lab, they grouped together bacteria with similar genetics that coexist in the same micro-habitat.
本发明提供一种利用超声和光谱技术组合成像和分析生物结构的设备。
The invention provides an apparatus for combined imaging and analyzing of a biological structure by means of ultrasonic and spectroscopic techniques.
碳水化合物的组合合成是一项新兴技术,该技术可以在短时间内合成大量用于进行生物活性筛选的寡糖及拟糖物。
Combinatorial synthesis of carbohydrates is the newly formed technique to synthesize and biologically screen large set of oligosaccharides and glycomimetics in a very short time.
碳水化合物的组合合成是一项新兴技术,该技术可以在短时间内合成大量用于进行生物活性筛选的寡糖及拟糖物。
Combinatorial synthesis of carbohydrates is the newly formed technique to synthesize and biologically screen large set of oligosaccharides and glycomimetics in a very short time.
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