赵永娜,李晓红,方正梅,李顺英,邵晓霞,东莨菪碱对吗啡诱发条件位置性偏爱重现大鼠杏仁核p-CREB及c-Fos表达的影响 位置性偏爱重现大鼠杏仁核p-CREB及c-Fos表达的影响 前言: 目的:探讨 东莨菪碱对 吗啡诱发条件位置性偏爱(condit ioned p lace preference, CPP)重现大鼠杏仁核(amygdala nucleus, Amy) cAMP反应元件结合蛋白(phosp
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条件性位置偏爱 conditioned place preference
条件性位置偏爱实验 Conditioned Place Preference ; CPP
的条件性位置偏爱 Conditioned Place Preference ; CPP
吗啡条件性位置偏爱 conditioned place preference
诱导的条件性位置偏爱 conditioned place preference ; CPP
大小鼠条件性位置偏爱 Conditioned Place Preference
条件性位置偏爱系统 Conditioned Place Preference Box ; CPP
分析条件性位置偏爱 Conditioned Place Preference
条件性位置偏爱模型 conditioned place preference
目的:探讨5-HT3型受体特异性拮抗剂奥丹西隆对吗啡诱导的条件性位置偏爱(CPP)效应的影响及其可能机制。
OBJECTIVE:To elucidate the effect of ondansetron(OND), a 5-HT3 receptor antagonist, on the morphine-induced conditioned place preference(CPP) in mice and its possible mechanism.
方法··:毁损依赖大鼠腹侧苍白球,利用条件性位置偏爱实验测定术前、术后依赖大鼠对注射吗啡侧的偏爱程度,评价腹侧苍白球在药物强化效应程度中的作用。
Method: Electrical lesions of ventral pallidum were done in 12 morphine dependent rats and the drug seeking behavior was measured by conditioned place preference paradigm.
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