必要时，涂一点蜂蜜，然后用绷带包扎。

In a pinch, dab on a little honey and then cover with a bandage.

youdao

这支队一败涂地。

The team was soundly defeated.

《牛津词典》

我们队被打得一败涂地。

Our team got taken to the cleaners.

《牛津词典》

Or in some cases they go to the dendrite of the neuron and they kind of put a paste over it so that the neurotransmitters can't connect.

有时这些药物会渗透到神经元的树突,这些药物就像是在树突上涂了一层涂料,使得神经递质无法将树突与轴突相连

耶鲁公开课 - 心理学导论课程节选