方法用不同剂量的阿司咪唑对小鼠灌胃，分别记录不同时间的心电图变化。
METHOD Recording the ECG of mice in different time after they were admistrated with astemizole in different dose in different time.
结论：西替利嗪治疗常年变应性鼻炎与阿司咪唑比较具有起效快、不良反应少的特点。
CONCLUSION: the effect of cetirizine in treating perennial allergic rhinitis is faster and the adverse reaction is less than those of astemizole.
结果阿司咪唑使多数小鼠心率减慢，PR间期和Q T间期延长，随剂量增加，甚至可引起完全性房室传导阻滞和窦性停搏。
RESULTS astemizole could slower the heart rate of mice, prolong P-R and Q-T interphase, even arise the complete AV block and sinus beat stop with the dose increase.
结果阿司咪唑使多数小鼠心率减慢，PR间期和Q T间期延长，随剂量增加，甚至可引起完全性房室传导阻滞和窦性停搏。
RESULTS astemizole could slower the heart rate of mice, prolong P-R and Q-T interphase, even arise the complete AV block and sinus beat stop with the dose increase.
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