目的研究和克服胰岛素在电致孔下经皮传输过程中在皮肤中的滞留，提高胰岛素的经皮渗透速率。
OBJECTIVE To investigate the entrapment of insulin in skin via electroporation, diminish the entrapment and enhance the transdermal delivery of insulin.
结果超过50%的胰岛素在电致孔经皮传输的过程中滞留于皮肤中，滞留量随脉冲时间常数的减小和胰岛素浓度的增加而增加；
RESULTS Over 50% insulin was entrapped in skin during transdermal delivery, and more insulin was entrapped with the shorter pulses and higher concentration of insulin in the solution.
结果超过50%的胰岛素在电致孔经皮传输的过程中滞留于皮肤中，滞留量随脉冲时间常数的减小和胰岛素浓度的增加而增加；
RESULTS Over 50% insulin was entrapped in skin during transdermal delivery, and more insulin was entrapped with the shorter pulses and higher concentration of insulin in the solution.
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