他们在20世纪80年代晚期发现，尽管一串线性氨基酸可以在试管中折叠成特定的三维形状，但蛋白质自身不能在细胞内完成这一过程。
In the late 1980s, they discovered that although a linear string of amino acids can fold into its proper three-dimensional shape in a test tube, the protein cannot do this on its own within a cell.
有大量的研究表明它们并不是很好的标志物，因为甲胎蛋白和其他两个标志物也仅仅在晚期癌症表达更加常见。
There is a good deal of data to suggest that they are not very good markers because alpha fetoprotein and these other two markers are also more common and more commonly expressed in advanced cancers.
妊娠中期的后期和妊娠晚期产检时血压和尿蛋白测量对先兆子痫的诊断很重要。
Measurement of blood pressure and urine protein at regular intervals in the late second and third trimesters is critical for diagnosis of preeclampsia.
在腺病毒载体的构建过程中，早期和晚期启动子的选择、构建以及去除末端蛋白(TP)、克隆末端序列是至关重要的。
The selection and cloning of early and late promoters and removal of adenovirus terminal protein (TP) are very important in construction of adenovirus vector.
目的：评价不同深静脉穿刺置管部位对恶性肿瘤晚期合并低蛋白水肿患者的安全性。
Objective:To evaluate the safety of different sites of intravascular catheterization by central venous puncture in patients of terminal malignant tumors accompanying hypoproteinemia.
过量血糖反应蛋白在组织中，以何种形式被称为晚期糖化终产物，或年龄的。
The excess in blood glucose reacts with proteins in tissues to form what are known as advanced glycation end products, or AGE's.
方法应用免疫组织化学方法对122例晚期NSCLC组织进行ERCC1、RRM1及BRCA1蛋白表达检测。
Methods The expression of ERCC1, RRM1 and BRCA1 protein in 122 cases of advanced NSCLC was detected by immunohistochemical methods.
结论血清甲状腺激素水平联合血清蛋白质等其他指标的检测，将有助于晚期癌症患者的预后判断。
Conclusions Detection of serum level of thyroid hormones combining with measure of serum proteins may contribute significantly to the prognosis of patients with advanced tumors.
其晚期基因L1结构蛋白是刺激机体产生中和抗体的主要抗原。
The L1 protein which coded by the late gene L1 of HPV18 is the main antigen which induces the neutralization antibody.
结果：牙胚发育过程中的蕾状期、帽状期、钟状晚期基质金属蛋白酶- 2 （MMP - 2 ）均有表达，但以钟状期前牙本质细胞的表达最明显。
RESULTS: The expression of MMP-2 could be found in bud stage , cap stage and later time of bell stage.
结果全部患儿住院早期以及中晚期血清白蛋白浓度、危重病评分之间均存在着差异，且有非常显著性意义（P<0.02，P<0.01）。
Results The levels of serum albumin and scores of serious illness remarkably decreased in dead cases. The differences did reach statistical significance(P<0.02, P<0.01).
总之，食物中的晚期糖基化终产物含量越高，血液中的晚期糖基化终产物水平就越高，C反应蛋白和其他一些炎症标记分子的水平就越高。
Overall, the higher the participants' consumption of foods rich in AGEs, the higher their blood levels of AGEs and the higher their levels of C-reactive protein and other biomarkers of inflammation.
目的：高迁移率族蛋白b1 (HMGB1)作为一种晚期炎症介质，介导了脓毒症和其他系统性炎症的致死性效应。
Objective: High mobility group box 1 protein (HMGB1) as a late-acting cytokine mediates lethality of sepsis and systemic inflammation.
因此，RIP1可能是一个核蛋白，与其他蛋白形成一个功能复合体，在花粉形成的晚期发挥重要作用。
Therefore, RIP1 is probably a nuclear protein that may form a functional complex with other proteins and carry out essential cellular and developmental roles during the late stage of pollen formation.
目的研究晚期糖基化终产物（AGE）修饰蛋白对人内皮细胞分泌单核细胞趋化蛋白1（MCP 1）的影响及其作用的信号传导途径。
Objective To investigate the effects of advanced glycation end products (AGE) on secretion of monocyte chemoattractant protein-1(MCP-1) by human endothelial cells and its signal transduction pathway.
结论：晚期肺癌和肺部良性疾病患者血浆纤维蛋白原水平与功能均高于正常对照，两组间差异有显著性。
Conclusion: Plasma fibrinogen concentration increases and its molecule function was abnormal in developing lung cancer and pulmonary benign disease. It was significantly difference in the two groups.
目的研究蚤休水提液对载脂蛋白E基因敲除小鼠晚期斑块的影响。
Objective: To study the effects of water extract from Paris Polyphylla Smith on advanced plaques in ApoE gene knockout mice.
它诱导细胞周期停滞在G1期晚期，可能诱导成骨蛋白2 (BMP - 2)。
It induces cell cycle arrest in late G1 phase and may induce bone morphogenic protein-2 (BMP-2).
到目前为止，肾功能下降被认为是与蛋白尿相关的晚期并发症。
Until now, such decline has been assumed to be a late-occurring event associated with proteinuria.
移植肾肾小球病(TG)通常被认为是伴随蛋白尿和肾功能减退的晚期慢性组织异常的一部分。
Transplant glomerulopathy (TG) usually has been described as part of a constellation of late chronic histologic abnormalities associated with proteinuria and declining function.
Pfizer的crizotinib专门攻击某种基因转录的蛋白，只有少于5%的非小细胞肺癌患者具有这种基因。 Roche的vemurafenib通过阻断基因B-RAF的变异体抵抗晚期黑色素瘤。
Pfizer's crizotinib attacks a protein encoded by a gene found in fewer than 5% of patients with non-small-cell lung cancer.
结论晚期氧化蛋白产物能通过氧化应激引起血管内皮细胞损伤。
Conclusion AOPP decreased endothelial cell viability via induction of oxidative stress.
一般而言，杀虫蛋白的含量在棉花生长发育的前期较高，到中期时有所下降，但到晚期时则又有回升。
Generally, insecticidal protein levels were high during the early stages of cotton growth; they declined in mid-season, and rebounded in late season.
结果：牙胚发育过程中的蕾状期、帽状期、钟状晚期基质金属蛋白酶- 2 （MMP - 2 ）均有表达，但以钟状期前牙本质细胞的表达最明显。
RESULTS: The expression of MMP-2 could be found in bud stage , cap stage and later time of bell stage. A high level of MMP-2 was confined to secretory odontoblas…
结果：牙胚发育过程中的蕾状期、帽状期、钟状晚期基质金属蛋白酶- 2 （MMP - 2 ）均有表达，但以钟状期前牙本质细胞的表达最明显。
RESULTS: The expression of MMP-2 could be found in bud stage , cap stage and later time of bell stage. A high level of MMP-2 was confined to secretory odontoblas…
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