• They're making that because you need this protein insulin, it's a hormone, and it's important for sugar metabolism in your body.

    它们产生胰岛蛋白是因为你需要它,胰岛素是一种激素,它在糖代谢中起着非常重要的作用

    耶鲁公开课 - 生物医学工程探索课程节选

  • A pancreas--cell in the pancreas, for example, needs to make insulin and so the gene for insulin is transcribed.

    举个例子,一个胰腺细胞,要分泌胰岛素,那么编码胰岛蛋白的基因就会被转录

    耶鲁公开课 - 生物医学工程探索课程节选

  • There are proteins, for example, on the surface of some cells that bind insulin and respond to the presence of insulin.

    比如说蛋白,有些细胞表面上的蛋白,捕获胰岛素并且对胰岛素进行应答

    耶鲁公开课 - 生物医学工程探索课程节选

  • Like we talked about with insulin; make large quantities of this recombinant viral protein, and use that as a vaccine.

    就像我们讲过的胰岛素,生成大量重组的病毒蛋白,并将其作为疫苗使用

    耶鲁公开课 - 生物医学工程探索课程节选

  • They put a gene like the insulin gene in place of the milk protein, but behind the promoter that is used to produce milk proteins.

    人们将产羊奶蛋白的基因,换成了胰岛素基因,在启动子后面的基因,原本是编码羊奶蛋白

    耶鲁公开课 - 生物医学工程探索课程节选

  • But that's not all, that protein insulin is made in the form of a long polypeptide that not - that's not always the final version of the protein.

    但这还没完,这个胰岛蛋白刚翻译完成时,还是一段长多肽的形式,还不是蛋白质的最终形式

    耶鲁公开课 - 生物医学工程探索课程节选

  • To make insulin, for example, your cells of your pancreas have to be transcribing that gene, it has to be processed, has to be translated into the protein insulin.

    举例来说,如果要合成胰岛素,你的胰腺细胞必须先转录那一段基因,然后进行加工,继而翻译成为胰岛蛋白

    耶鲁公开课 - 生物医学工程探索课程节选

  • Here's an example where we'd like to make insulin, or having the insulin gene would be useful, but if we could take the insulin gene and make many copies of the insulin protein that would be a very useful thing.

    例子就是我们人工制造胰岛素,胰岛素基因就很有用,但如果我们可以用胰岛素基因,复制很多胰岛蛋白,这将会是非常有裨益的一件事

    耶鲁公开课 - 生物医学工程探索课程节选

  • It gets converted into a protein, insulin, only in those cells that are able to make the RNA that are able to express the protein.

    只有在能表达,胰岛蛋白RNA的细胞里,基因才能指导产生胰岛

    耶鲁公开课 - 生物医学工程探索课程节选

  • In this case, it says it's GCSF, but it could also be insulin, for example.

    在这个例子中,目标蛋白基因被称为GCSF,但它也可以是,例如胰岛素基因

    耶鲁公开课 - 生物医学工程探索课程节选

  • A section of DNA that is responsible for encoding a gene, let's say it's the insulin gene for example, might be some stretch of DNA on a certain chromosome inside your cells, inside the cells of the pancreas.

    一段编码蛋白的DNA序列,我们就拿编码胰岛素的基因来举个例子,它也许是一段DNA基因序列,位于你胰腺细胞里的,某条染色体上

    耶鲁公开课 - 生物医学工程探索课程节选

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