• We're going to talk about this kind of non-covalent interaction more when we talk about the immune system, because one example of ligand and receptors that's important in the immune system are antigens - foreign molecules, and antibodies - molecules that we produce.

    当我们讲到免疫系统的时候,会更详细地谈到这种非共价化合反应,因为在免疫系统中,一个重要的配体受体结合反应,就是抗原,即外源分子,与抗体,这个人体自身产生的分子结合

    耶鲁公开课 - 生物医学工程探索课程节选

  • These cells can now kill cells that have the correct signature, and the signature is MHC-1 with this foreign antigen associated with it.

    而这些细胞现在可以杀伤带标记的细胞,这些标记就是MHC-1表面受体,和与其相联的异己抗原

    耶鲁公开课 - 生物医学工程探索课程节选

  • We talked about host cells that are perhaps infected with a virus, displaying pieces of that virus, antigenic pieces of that virus in the context of a surface receptor called MHC-1, presenting that.

    我们说到过,可能受到病毒感染的宿主细胞,表现出病毒的一部分特征,病毒的抗原部分,其表面受体称为主要组织相容性抗原-1,MHC-1负责呈递抗原

    耶鲁公开课 - 生物医学工程探索课程节选

  • Immune cells recognize it, and they recognize it by a very special form of receptor-ligand interaction where the ligand is MHC1 with the foreign antigen and the receptor is a receptor called the T-cell receptor complex.

    免疫细胞识别出染病细胞,通过一种特殊形式的,受体配体协作机制识别出来,其中的配体是同,外源抗原共同出现的MHC1,而这其中受体是T细胞受体复合体

    耶鲁公开课 - 生物医学工程探索课程节选

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