These difficulties place Poe's writing outside the main body of American literature.

VOA: special.2010.10.31

It is also important to put these resources in places that help us cultivate capacity, the capacity to deal with these difficulties and hardships when they arise and they will arise.

同样重要的是，投入资源,帮助我们培养自身能力，应对困难和艰辛的能力,这些困难一直存在并会继续出现的。

哈佛公开课 - 幸福课课程节选

I think that would help solve a lot of the medical difficulties that people have these days.

我认为这种办法可以帮助解决现在困扰人们的许多医学难题。

生物克隆是热点问题 - SpeakingMax英语口语达人

Let me reassure you that the government will meet those challenges and overcome these difficulties."

VOA: standard.2010.05.21

Yet,he says,he is convinced that the Czech Republic can cope with these difficulties.

VOA: standard.2009.03.25

But guess what? In the last decade weve been able to produce, in spite of all these difficulties, health workers in Mogadishu, in a hospital in Banadir University.

VOA: standard.2009.12.05

We are ready for difficulties and we know these difficulties.

VOA: standard.2010.05.28