In this article, we review PK/PD investigation of fluoroquinolones, and give a summary of PK/PD parameter of moxifloxacin and some other fluoroquinolones.
本文简要回顾了部分氟喹酮类药物的PK/PD研究，并对莫西沙星等主要氟喹诺酮类药物PK/PD参数进行总结。
Objective To determine the PK/PD parameters which is more dependent on the inhibition of resistant mutants using vitro pharmacodynamic model.
目的通过体外药效学模型探讨预测抑制细菌耐药突变的PK/PD参数折点。
Parametric method which based on the theory of "effect compartment" suggested by Sheiner (1979) et al includes ten PK models and three PD models.
参数法包括十个药动学模型和三种药效学模型，可以同时求算药动学和药效学参数；
Parametric method which based on the theory of "effect compartment" suggested by Sheiner (1979) et al includes ten PK models and three PD models.
参数法包括十个药动学模型和三种药效学模型，可以同时求算药动学和药效学参数；
应用推荐