It suggested that the LDL receptor in human fetal liver may play a key role in the regulation of the serum cholesterol levels in the fetus during gestation.
这一结果提示,在胎儿发育过程中,肝脏ldl受体对血胆固醇水平调节起着关键的作用。
To understand intron 15 of human LDL receptor gene, the DNA fragments from exon 15 to exon 16 and the 3' end of intron 15 were amplified with long chain PCR and anchored PCR.
为了解人类LDL受体基因内含子15的遗传背景,利用长链PCR和锚定PCR分离了LDL受体基因外显子15-内含子15-外显子16和内含于15的3’末端片段。
Conclusion: HGF can up-regulate expression of LDL receptor in mesangial cells and increase mesangial cells uptake of LDL, so HGF may play a role in lipid-induced kidney injury.
结论:HGF通过促进系膜细胞表达LDL受体,增加系膜细胞对LDL的摄取,可能参与了脂质肾损伤过程。
The LDL receptor defects cause the elevation LDLcholesterol in plasma. This is the main reason for atherosclerosis and is closely related to the risk of coronary heart disease (CHD).
LDL受体介导的低密度脂蛋白胆固醇水平的升高是致动脉性粥样硬化的主要原因,与冠心病危险性的增加密切相关。
Objective to investigate the effects of oxidized low-density lipoprotein receptor 1 (LOX-1) on secretion of adhesive molecules mediated by ox-LDL in human umbilical endothelial cells (HUVECs).
目的探讨血凝素样氧化低密度脂蛋白受体1 (LOX - 1)在氧化低密度脂蛋白(ox - LDL)诱导血管内皮细胞粘附分子表达中的作用。
Early glycated low density lipoprotein (LDL) was not recognized by this receptor. AGEP BSA elevated cytosolic free calcium in a concentration dependent manner.
通过该受体介导,平滑肌细胞可内化、代谢AGEP.AGEP使胞浆游离钙呈浓度依赖性升高;
The mechanisms are probably that zinc can regulate the receptor of liver cell for HDL-C and LDL-C, compete with arsenic for -SH binding and precipitate the excretion of arsenic.
可能与锌调节肝细胞相应受体、与砷竞争性结合琉基、促进砷的排泄有关。
These results showed that Da Huai Mixture could promote LDL catabolisms by both receptor dependent and independent pathways.
结果提示:大槐合剂可同时促进受体和非受体途径清除LDL的作用。
For instance, familial hypercholesterolemia (FH) typically results from mutations in LDLR encoding the low-density lipoprotein (LDL) receptor.
例如,家族性血胆脂醇过多症(FH)通常起源于编码低密度脂蛋白(LDL)受体的LDLR突变。
LOX-1 was identified from endothelial cells as the main receptor specially recognizing and uptaking the ox-LDL, LOX-1 plays a key role in the endothelial dysfunction triggered by ox-LDL.
凝集素样氧化低密度脂蛋白受体(LOX - 1)是内皮细胞膜上特异性识别摄取ox - LDL的最主要受体,LOX - 1在介导ox - LDL导致内皮功能紊乱的过程中起关键作用。
These suggest that RAP may take part in the process of lipid metabolism in many tissues for RAP is chaperone of LDL-receptor family.
推测RAP参与许多组织器官的代谢过程,尤其可能是与脂蛋白代谢有关的重要物质。
These suggest that RAP may take part in the process of lipid metabolism in many tissues for RAP is chaperone of LDL-receptor family.
推测RAP参与许多组织器官的代谢过程,尤其可能是与脂蛋白代谢有关的重要物质。
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