After 240 weeks of therapy, the cumulative rates of HBV polymerase mutations, virologic resistance, and clinical resistance were 29%, 20%, and 11%, respectively.
经过240周的治疗后，HBV聚合酶的蓄聚率、病毒的耐药率和临床耐药率分别是29%，20%和11%。
In both of these clinical situations, health care staff should respond with a high level of suspicion that oseltamivir resistance has developed.
针对这两种临床病例，医务人员应该高度怀疑已产生对奥司他韦的耐药性。
OBJECTIVE: To study the common pathogenic bacteria and their drug resistance so as to provide strong evidences for clinical rational use of antibacterials.
目的：掌握我院患者常见病原菌及其耐药情况，为临床合理应用抗菌药物提供有力证据。
Objective to realize the clinical distributing and drug resistance change of MRS in different periods in order to provide some references for clinical rational drug use.
目的了解不同时期耐甲氧西林葡萄球菌(MRS)临床分布及耐药性变迁情况，为临床合理用药提供参考。
Increasing resistance to FQs in enterococci has been noted with these agents broadly used in clinical medicine.
随着氟喹诺酮类抗菌药在临床广泛应用，肠球菌对其耐药性迅速增长。
OBJECTIVE To analyze pathogenic bacterium distribution and antibiotic resistance of our hospital, and provide scientific basis for clinical rational using of antibiotics.
目的分析医院尿路感染常见的病原菌分布及细菌对抗菌药物耐药情况，为临床合理使用抗菌药物提供科学依据。
Using this data, we seek to apply pharmacodynamic principles to assist clinical practice for suppressing the emergence of resistance.
基于这些数据，我们寻找到抑制耐药辅助临床的药效学原则。
OBJECTIVE:To investigate drug resistance status of meticillin-resistant Staphylococcus(MRS)in our hospital for providing reference for clinical rational use of drug.
目的：了解我院耐甲氧西林葡萄球菌（MRS）的耐药现状，为临床合理用药提供依据。
OBJECTIVE to investigate the major pathogenic bacteria and drug resistance in the infantile septicemia and to provide laboratory evidence for clinical diagnosis and treatment.
目的了解和探讨婴幼儿败血症的主要病原菌及耐药性现状，为临床诊断与治疗提供实验室依据。
Conclusion Clinical doctors should pay attention to the detection and drug resistance of pathogens in urinary system infection, control nosocomial urinary infection and use antibiotics reasonably.
结论临床医师应重视尿路感染病原菌及其耐药性检测，控制医院内尿路感染，合理使用抗生素。
Drug resistance of mycoplasma is severe. Culture and drug susceptibility testing of mycoplasma are important for clinical therapy.
支原体感染的耐药情况严重，在临床工作中同时进行支原体培养和药敏试验对临床用药具有重要意义。
CONCLUSIONS Resistance detection of bacteria periodically has an important significance to clinical treatment with drugs.
结论定期系统地进行细菌耐药监测，对临床合理用药具有重要的指导意义。
Understanding biofilm formation by fungi and the impact of factors and resistance mechanisms to combat fungal infections has great clinical significance.
认识真菌生物膜及其形成的影响因素和耐药机制对于防治临床真菌感染有着重大意义。
OBJECTIVE To study the resistance of clinical bacterial isolates in Hubei area.
目的调查湖北地区临床分离菌对抗菌药物的耐药状况。
CONCLUSION: the clinical physicians should understand the characteristics of drug resistance and rationally choose the antibiotics.
结论：临床应了解细菌对抗生素的耐药特点，合理选用抗生素。
Objective To study the effect of the upper airway compliance on the airway resistance (r aw) and its clinical significance.
目的探讨上气道顺应性对气道阻力测值的影响及其临床意义。
Objective: It is to investigate the clinical significance of survey technique of nasal airway resistance in asthma and the mechanism of asthma.
目的：探讨鼻气道阻力测定技术在哮喘中的临床价值和哮喘的发病机理。
Objective To understand in hospital the distribution of lower respiratory tract infection of pathogens and drug resistance for clinical basis for rational use of antimicrobial agents.
目的了解我院下呼吸道感染病原菌的分布及耐药情况，为临床合理应用抗菌药物提供依据。
Clinical non cross resistance had been demonstrated between TPT and cisplatin or paclitaxel.
临床试验表明，TPT与顺铂和紫杉醇无交叉耐药性。
OBJECTIVE To investigate the distribution of clinical bacterial isolates and the change in antibiotic (resistance) spectrum.
目的了解临床分离病原菌种类分布及对抗菌药物耐药性的变化。
The results demonstrated that tetrandrine can reverse the harringtonine resistance in the human promyelocytic leukemia HL60 cells and will be worthful for further clinical research.
结果表明：粉防己碱能逆转人早幼粒白血病HL60耐药细胞对三尖杉酯碱的耐药性，值得临床上进一步研究。
Objective: To investigate and analyze the bacterial resistance of clinical isolates.
目的：分析临床分离细菌的耐药性情况。
Drug resistance is the main restriction factor for clinical usage of taxanes.
耐药是影响紫杉类药物临床疗效的重要因素。
OBJECTIVE To study the flora distribution and drug resistance dymamics of clinical isolated bacteria in Yuxi city.
目的了解本地区临床感染细菌的菌群分布和耐药性变迁情况。
The purpose of the analysis of the high altitude and the type of yeast-like fungi resistance characteristics for clinical use of antifungal agents to provide a reasonable basis.
目的分析高海拔地区酵母样真菌种类及其耐药性特点，为临床合理使用抗真菌药物提供依据。
In this article we reviewed the advances in clinical study of imatinib including its mechanism of resistance, adverse events, life quality study and cost-effective analysis, etc.
本文从耐药机制、不良反应、生活质量考察、药物经济学成本-效用分析等方面综述了其最新临床研究进展。
Objective: To understand the clinical features and resistance of Burkholderia cepacia in intensive care unit.
目的：研究危重病监护病房内洋葱伯克霍尔德菌感染的临床特征和细菌的耐药性。
Objective To study the clinical application of DNA chip for common Gram-positive bacteria identification and drug resistance detection.
目的利用基因芯片技术进行常见革兰阳性细菌的细菌鉴定和耐药性检测。
Objective To study the clinical application of DNA chip for common Gram-positive bacteria identification and drug resistance detection.
目的利用基因芯片技术进行常见革兰阳性细菌的细菌鉴定和耐药性检测。
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