They have lots of pharmacological abilities, such as hepatoprotection and chemotherapy, but their clinical use is limited by poor aqueous solubility.
它们有很多药理活性,如肝保护、化疗辅助等,但临床应用受到了低水溶性的限制。
Aim: to formulate the spray-dried emulsion of ZLR-8, a new NO-donor nonsteroidal anti-inflammatory drug with poor absorption and sparingly aqueous solubility.
目的:对极难溶性的氮氧供体型非甾体抗炎药zlr - 8喷雾干燥乳剂进行处方研究。
Abstract: Lutein has many conjugated double bonds, which lead to poor aqueous solubility and stability and constrain its application in commercial and clinical fields heavily.
摘要:叶黄素分子中含有多个共轭双键,导致其水溶性和稳定性较差,极大地限制了其生物利用度。
The amphipathic super-paramagnetic and magnetically resonant contrast agent integrates the advantages of stability, aqueous solubility and biocompatibility, and reduces the toxicity.
集稳定性、水溶性和生物相容性的优点于一体,并降低了毒性。
Results the aqueous solubility of quercetin was greatly increased (about 37 folds) by inclusion technique, and the initial dissolution rate was markedly improved (10 folds) in the first 5 min.
结果所制备的包合物溶解度较槲皮素纯品增加约37倍,5分钟的溶出百分率较槲皮素纯品提高近10倍。
It has the advantages of high active oxygen content, weak acidity of the aqueous solution and good solubility in organic solvent in comparison with other solid peroxides.
同其它过氧化物相比,它具有活性氧含量高,水溶液呈弱酸性及能溶于有机溶剂的特点。
The walnut chip solubility and emulsification ability after aqueous extraction of walnut oil and the affecting factors were studied.
研究了水代法提取核桃油后蛋白粕的溶解度、乳化特性及其影响因素。
For resolving the lack of solubility data terephthalic acid in aqueous acetic acid, a method of determining the solubility at high temperature was developed.
针对对苯二甲酸工业中的溶解度基础数据缺乏的问题,提出了一种测定高温下对苯二甲酸在醋酸水溶液中的溶解度的方法。
The amino groups of the gelatin are the amenable sites for modification in aqueous solution. Benzoylation of the gelatin with pathalic anhydride can change the solubility.
通过明胶活泼氨基的酰化反应,可以接入憎水性的芳基改变明胶的水溶性;
The solubility curve of sodium nitrate in pure dimethyl sulfoxide and in DMSO aqueous solution are given.
给出了硝酸钠在纯二甲基亚砜及二甲基亚砜水溶液中溶解度曲线。
The result of performance test shows that the solubility of prepared waterborne epoxy resin decreases in organic solvent and increases in alkaline aqueous solution.
性能测试结果表明,所制的水性环氧树脂在有机溶剂中的溶解性变差,在碱性水溶液中的溶解性增强;
Measure the solubility of a compound in aqueous solution.
测量在溶液中化合物的溶解度。
While the steroid in a very low solubility in aqueous media, traditional biological conversion reaction carried out in the water phase are often restricted on available substrates.
传统生物转化反应在水相中进行,而甾体在水介质中溶解度极低,经常受到可利用底物的限制。
The results show that the solubility of DCH18C6 in an aqueous solution depends not only upon the acidity, the salt content, and the temperature of the solution, but also upon its own existing form.
实验结果表明,DCH18C6在水溶液中的溶解度不仅与溶液的酸度、含盐量有关,而且还与冠醚的形态有关。
The solubility of CH331 in outer aqueous phase played a significant role in encapsulation efficiency and in vitro drug release of microspheres.
CH331在外水相中的溶解度影响微球的包封率和体外释药行为。
Dissolution Capacity of Hydrophobic Drugs in Aqueous Solution--Solubility and Diffusion Gibbs Free Energy;
这种的溶解度可能与非水合物的溶解度有明显的不同。
Dissolution Capacity of Hydrophobic Drugs in Aqueous Solution--Solubility and Diffusion Gibbs Free Energy;
这种的溶解度可能与非水合物的溶解度有明显的不同。
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