HIF-1 plays crucial roles in oxygen homeostasis, cell energy metabolisms, tumor angiogenesis and metastasis, cell proliferation and apoptosis.
其在维持氧稳定、细胞能量代谢、肿瘤血管生成及转移、细胞增殖与凋亡等诸多方面起着重要作用。
Recently, it was found that chemokines and their receptors were involved in proliferation, angiogenesis and metastasis of various types of cancer cells.
近年来研究发现，趋化激素与其受体在癌细胞的增生、血管新生与转移上扮演重要的角色。
Vascular endothelial growth factor (VEGF) family is vital for angiogenesis and metastasis of cancer. Studies demonstrate that blockade of VEGF activity can control the growth of tumor.
血管内皮生长因子(VEGF)家族在肿瘤血管生成与转移中起关键作用，从不同途径阻断vegf的生物学作用可以达到治疗肿瘤的目的。
Angiogenesis is the basis of tumor growth and metastasis.
新生血管是肿瘤生长和转移的基础。
Angiogenesis is the essential factor for tumor growth and metastasis.
血管新生是实体瘤生长和转移的必要条件。
Osteopontin is a glycoprotein involved in inflammation, angiogenesis, and metastasis, and has been found in higher levels in cancer patients with metastatic disease.
骨桥蛋白是一种参与炎症、血管生成和转移的糖蛋白，研究发现其在发生癌症转移的病人中血中表达水平较高。
Tumor associated angiogenesis plays a pivotal role in the growth and metastasis of tumors.
肿瘤血管生成在肿瘤的生长和转移中起着重要的作用。
Angiogenesis is the basis of tumor growth, invasion, metastasis and recidivism.
血管生成是肿瘤生长、侵袭、转移、和复发的基础。
Matrix metalloproteinases (MMPs) has been viewed as a promising target in tumor therapy in recent years due to their key role in tumor growth, angiogenesis, invasion and metastasis.
近几年来，基质金属蛋白酶因在肿瘤的生长、转移和血管生成等多个环节中发挥着重要作用而成为肿瘤治疗研究中引人注目的新靶点。
Angiogenesis is the basis of growth and metastasis of malignant tumor.
血管生成是恶性肿瘤生长和转移的基础。
Objective to study the effects of angiogenesis inhibitor SU5416on the growth and metastasis of colon cancer in vivo.
目的研究血管生成抑制因子su 5416对结肠癌生长和转移的抑制作用。
Matrix metalloproteinases (MMPs) has been viewed as a promising target in tumor therapy due to their key role in tumor growth, angiogenesis, invasion and metastasis.
基质金属蛋白酶(MMP)因其在肿瘤的生长、转移和血管生成等多个环节中发挥着重要作用而成为肿瘤治疗研究中引人注目的靶点。
Glycans regulate tumour proliferation, invasion, haematogenous metastasis and angiogenesis.
聚糖能调节肿瘤增殖、侵袭、转移和血管生成。
Objective: To evaluate angiogenesis depending characteristics of carcinoma proliferation and metastasis.
前言：目的：研究兔肝肿瘤增生和转移的血管依赖特性。
Objective To explore the relationship between angiogenesis and tumor metastasis and prognosis by studying the angiogenesis in colorectal carcinoma tissues and metastasized tissues.
目的研究大肠癌与转移癌组织的血管生成情况，探讨血管生成与肿瘤转移和预后的关系。
Tumor angiogenesis inhibitor is a class of new drugs that can destroy or inhibit tumor neovascularization, and can effectively block the growth and metastasis of cancer.
肿瘤血管生成抑制剂是一类能破坏或抑制血管生成，有效地阻止肿瘤生长和转移的药物。
Angiogenesis is the key step in tumors proliferation and metastasis, which depends on the net balance between endogenous stimulators and inhibitors.
血管形成是实体肿瘤增殖和转移的关键步骤，这一过程依赖于内源性刺激因子和抑制因子之间的平衡。
Objective to explore the co operative inhibitory effect of antisense VEGF gene and endostatin gene transfection on tumor angiogenesis, tumor growth and metastasis of lung cancer.
目的探讨反义vegf基因和内皮抑素基因联合转染在抑制肿瘤血管生成和肿瘤生长转移中的作用。
Objective to study the effect of angiogenesis inhibitor SU6668 on the growth and metastasis of gastric cancer in SCID mice.
目的研究血管生成抑制剂SU6668对胃癌生长和转移的抑制作用。
Objective To study the effects of VCAM-1 (Vascular cell adhesion molecule-1)on the angiogenesis, growth and metastasis of gastric cancer.
目的研究胃癌瘤体中血管细胞粘附分子（V CAM 1）对胃癌的血管生成、生长、转移的影响。
VEGFR2, which plays crucial roles in angiogenesis induced by tumor, is a new ideal target for inhibiting development and metastasis of tumor.
VEGFR2介导肿瘤诱导的血管生成作用，是抑制肿瘤生长和转移的新靶点。
Tumor angiogenesis, resulting from the imbalance of angiogenic cytokines and angiogenesis inhibitors, is crucial for tumor growth and metastasis.
肿瘤血管生成是肿瘤生长转移的关键步骤，是促血管生成因子和抑制因子作用失衡的结果。
Objective: to investigate the role of vascular endothelial growth factor (VEGF) on angiogenesis, tumor growth and metastasis in osteosarcoma, and its clinical significance.
目的：研究血管内皮生长因子(VEGF)对骨肉瘤血管生成、生长、转移及预后的影响。
The above features render this animal model useful in studying tumor invasion and metastasis, and tumor angiogenesis as well.
这对于研究肿瘤转移、浸润以及肿瘤血管生成具有一定意义。
Angiogenesis is a key limiting step in tumor growth and metastasis. The control of angiogenesis has emerged as an important mechanism of suppressing tumor growth.
血管生成是肿瘤生长转移过程中的一个关键环节，因此控制血管生成成为抑制肿瘤生长的重要途径之一。
Conclusions LS can significantly inhibit growth, metastasis and angiogenesis of pancreatic cancer.
结论硫酸昆布多糖对肿瘤生长、转移、血管生成有明显抑制作用。
Conclusions? Tumor angiogenesis plays an important role in tumor invasion and metastasis. MVD may serve as a significant prognostic indicator in EOC.
结论？肿瘤组织的血管生成在卵巢癌的浸润性生长及转移方面起着重要作用，MVD可作为判断恶性卵巢肿瘤预后的一项重要指标。
Now it is known that the tumor proliferation and metastasis depend on angiogenesis.
目前认为肿瘤的增殖和转移依赖于血管新生。
Now it is known that the tumor proliferation and metastasis depend on angiogenesis.
目前认为肿瘤的增殖和转移依赖于血管新生。
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