罪魁祸首就是胸腺基质淋巴生成素(简称TSLP),这是一种由受损的皮肤分泌的信号分子,受损的皮肤引起身体强烈的免疫反应以便对抗入侵细胞。
The culprit is thymic stromal lymphopoietin (TSLP), a signalling molecule secreted by damaged skin cells which elicits a strong immune response from the body to fight off invaders.
罪魁祸首就是胸腺基质淋巴生成素(简称TSLP),这是一种由受损的皮肤分泌的信号分子,受损的皮肤引起身体强烈的免疫反应以便对抗入侵细胞。
The culprit is thymic stromal lymphopoietin (TSLP), a signalling molecule secreted by damaged skin cells which elicits a strong immune response from the body to fight off invaders.
接着,他们用另外的工程删除在肺部接收胸腺基质淋巴细胞生成素的感受器分子的基因。
Then they used additional engineering to delete the gene for the receptor molecule which picks up TSLP in the lungs.
因此,新的想法就是刺激免疫系统中的T淋巴细胞,让它迅速杀死受到感染的细胞,使之来不及生成新的病毒,以此限制病情恶化。
So the idea is to spur other soldiers of the immune system called t cells to quickly kill the infected cells before they could make new viruses. That would limit disease severity.
在长时间里,可能发明出一种药物,就是能抑制胸腺基质淋巴细胞生成素的产物或者干扰肺部里的胸腺基质淋巴细胞生成素感受器分子。
In the longer term, it might be possible to devise drugs that inhibit the production of TSLP or interfere with TSLP-receptor molecules in the lungs.
第三,他们设计让老鼠在它们没有其他皮肤问题的情况下,在它们的皮肤里产生高水平的胸腺基质淋巴细胞生成素。
Thirdly, they engineered mice to produce high levels of TSLP in their skin in the absence of other skin problems.
目的研究胰腺癌淋巴管生成的机制、分布特征及其与胰腺癌临床病理学的关系。
Purpose To study the mechanism of lymphangiogenesis, its distributing character and relation with the clinicopathological features in human pancreatic cancer.
结论乳腺癌细胞可能通过活跃的淋巴管生成加速肿瘤的生长和转移。
Conclusion Breast cancer has active lymphangiogenesis which might contribute to its growth and metastasis.
现就近年来肿瘤淋巴管生成与转移的研究进展作一综述。
In recent years, is now on the tumor lymphangiogenesis and the transfer of the research are reviewed.
传语VEGF-D在乳腺癌中具有一定的诱导淋巴管生成的作用,并与肿瘤的淋巴侵袭转移及预后相关。
VEGF-D may induce lymphangiogenesis, and may be associated with lymph node invasion and prognosis in breast cancer.
信号系统是淋巴管生成或扩张的信号通路,与肿瘤淋巴管的生成密切相关。
VEGF-C/ VEGFR-3 (FLT-4) signalling which is mediated of lymphogenesis or dilation of lymphatics is closely correlated with lymphogenesis of tumor.
观察肿瘤抗原负载后诱导特异性细胞毒T淋巴细胞生成和对肿瘤细胞杀伤作用。
The effects of DCs pulsed with tumoral antigens on cytotoxic T lymphocytes(CTLs) inducement and growth inhibition of YTMLC cells were assayed.
肿瘤微环境中存在着大量的炎症细胞和淋巴管生成。
There are considerable inflammatory cells and lymphangiogenesis existing in tumor microenvironment.
结论肺内淋巴液的生成可能以小泡转运系统为主,肺巨噬细胞及白细胞迁移入淋巴管的通道可能是位于细胞连接处的一侵蚀性通道。
Conclusion Vesicles transportation might be the main pathway of lymph formation in lung, the lymphatic passage through which pulmonary macrophage and leukocyte pass might be a erosive passage.
目的:探讨上皮性卵巢癌组织中血管内皮生长因子a (VEGF - A)与肿瘤内淋巴管生成及淋巴结转移的关系。
Objective to investigate the relationship between expression of vascular endothelial growth factor a (VEGF-A) and lymphangiogenesis and lymph node metastasis.
目的探讨血管内皮生长因子c在直肠腺癌淋巴管生成中的作用。
Objective to investigate the effects of vascular endothelial growth factor-C (VEGF-C) on lymphangiogenesis in adenocarcinoma of rectum.
PEDF低表达和VEGF高表达可能是胃癌组织内微血管生成的分子基础,是促进胃癌细胞发生淋巴及血道转移的重要因素。
Lower PEDF and higher VEGF expression might be the molecular basis of angiogenesis in gastric carcinoma tissue and play an important role in lymphatic and blood metastasis of gastric carcinoma.
在淋巴结内定植生成转移灶。
目的探讨肺腺癌肿瘤相关巨噬细胞(TAM)浸润与淋巴管生成、患者生存的关系。
Objective To examine the relationship between tumor-associated macrophages (TAMs) infiltration and the density of lymphangiogenesis or the patients' clinical outcome in lung adenocarcinoma.
采用划线法和MTT法观察血管生成抑制素和反应停对淋巴管内皮细胞增殖和游走的影响。
Scraping line method and MTT were used to observe the effect of angiostatin and thalidomide on proliferation and migration of LEC.
提示耳蜗蜗管外壁ANP对内耳淋巴液的生成可能起着重要的作用;
The results suggest that ANP of the external wall of the cochlear duct may play an important role in the formation of endolymphe.
炎症细胞、促炎细胞因子和COX - 2等在肿瘤淋巴管生成过程中发挥了重要作用。
Inflammatory cells, proinflammatory cytokines and COX-2 play an important role in the process of lymphangiogenesis.
目的:血管内皮生长因子C(VEGF-C)属于血管内皮生长因子(VEGF)家族成员,被认为是目前发现的唯一特异性淋巴管生成因子。
Objective:Vascular endothelial growth factor C(VEGF-C) recently has been identified as a new member of the VEGF family and is considered as the single specific lymphangiogenic factor.
本文采用小鼠碳粒廓清、植物血凝素(PHA)诱导淋巴细胞转化,以及血清溶血素和抗体生成细胞测定等实验,研究南美植物玛咖的乙醇提取物对正常小鼠免疫功能的影响。
Oral administration of ethanol extract of Maca significantly increased the rate of transformation of lymphocyte induced by PHA and it also promoted production of hemolysin in serum and an.
本研究目的旨在观察脂质体介导的VEGF - C反义寡核苷酸对肺癌裸鼠皮下种植瘤模型微淋巴管生成的影响。
The aim of this article is to investigate the effects on lymphangiogenesis of orthotopic implantation of lung cancer in nude mice with antisense oligonucleotides of VEGF-C.
现就肿瘤淋巴管生成分子机制及其调控及与淋巴转移、临床预后的关系进展作一综述。
Here we will review the molecular mechanisms of lymphangiogenesis and the relation of lymphangiogenesis with lymphatic metastasis and...
手术病人术后2天和7天外周血单个核细胞(PBMC)的T淋巴细胞转化及白介素2 (il2)的生成均明显降低。
T lymphocyte transformation and interleukin 2 (IL 2) production of peripheral blood mononuclear cell (PBMC) in operated patients were decreased following 2 and 7 days post operation.
目的比较淋巴管内皮细胞对乳腺癌和骨肉瘤生长和转移的影响,分析淋巴管生成对肿瘤生长和转移影响的相关机制。
Objective To compare growth and metastasis of breast cancer cell and osteosarcoma cell influenced by co-inoculating human lymphatic endothelial cell (HLyEC), and to analyze its mechanisms.
肿瘤微淋巴管的生成对肿瘤的淋巴转移有着重要意义,肿瘤细胞的转移影响患者的预后。
The genesis of tumor micro-1ymphatic vessel has vastly significance for the tumor lymphatic metastasis, The metastasis of tumour cells could affect the prognosis of patients.
肿瘤微淋巴管的生成对肿瘤的淋巴转移有着重要意义,肿瘤细胞的转移影响患者的预后。
The genesis of tumor micro-1ymphatic vessel has vastly significance for the tumor lymphatic metastasis, The metastasis of tumour cells could affect the prognosis of patients.
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